The quality and maturation of an oocyte not only play decisive roles in fertilization and
embryo success, but also have long-term impacts on the later growth and development of …

During folliculogenesis, the oocyte and surrounding cumulus cells form an ensemble called
the cumulus-oocyte complex (COC). Due to their interdependence, research on the COC …

Women with diminished ovarian reserve (DOR) have reduced fertility, but the underlying
regulation of ovarian function remains unknown. Although differential microRNA (miRNA) …

High mitochondrial oxidative phosphorylation (mt-OXPHOS) levels are required to supply
the ATP necessary for follicle-stimulating hormone (FSH)-induced granulosa cell …

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among
reproductive-age women, affecting up to 15% of women in this group, and the most common …

Simple Summary In vitro embryo production using oocytes from prepubertal cattle and
buffalo collected by laparoscopy can be used to produce embryos from genetically superior …

Cadmium (Cd) is ubiquitous in our environment and can easily bioaccumulate into the
organism after passage through the respiratory and digestive tracts. Long-term exposure to …

Metabolic oligosaccharide engineering (MOE) is a classical chemical approach to perturb,
profile and perceive glycans in physiological systems, but probes upon bioorthogonal …

Aims Some studies have shown that mesenchymal stem cells (MSCs) and their derived
extracellular vesicles (MSC-EVs) can restore ovarian function in premature ovarian failure …

The quality and developmental capacity of oocytes derived from in vitro maturation (IVM)
remain unsatisfactory, which greatly impairs the efficiency and application of embryo …