Molecular biomarkers in localized prostate cancer: ASCO guideline

SE Eggener, RB Rumble, AJ Armstrong… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE This guideline provides recommendations for available tissue-based prostate
cancer biomarkers geared toward patient selection for active surveillance, identification of …

Cancer of the prostate: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

C Parker, S Gillessen, A Heidenreich… - Annals of …, 2015 - annalsofoncology.org
Subclinical prostate cancer is common in men> 50 years of age. Population-based
screening of men aged between 55 and 69 years, using prostate-specific antigen (PSA) …

Contemporary update of a multi-institutional predictive nomogram for salvage radiotherapy after radical prostatectomy

RD Tendulkar, S Agrawal, T Gao… - Journal of Clinical …, 2016 - ascopubs.org
Purpose We aimed to update a previously published, multi-institutional nomogram of
outcomes for salvage radiotherapy (SRT) following radical prostatectomy (RP) for prostate …

[HTML][HTML] Discovery and validation of a prostate cancer genomic classifier that predicts early metastasis following radical prostatectomy

N Erho, A Crisan, IA Vergara, AP Mitra, M Ghadessi… - PloS one, 2013 - journals.plos.org
Purpose Clinicopathologic features and biochemical recurrence are sensitive, but not
specific, predictors of metastatic disease and lethal prostate cancer. We hypothesize that a …

High-risk prostate cancer—classification and therapy

AJ Chang, KA Autio, M Roach III, HI Scher - Nature reviews Clinical …, 2014 - nature.com
Approximately 15% of patients with prostate cancer are diagnosed with high-risk disease.
However, the current definitions of high-risk prostate cancer include a heterogeneous group …

Adjuvant radiotherapy versus wait-and-see after radical prostatectomy: 10-year follow-up of the ARO 96–02/AUO AP 09/95 trial

T Wiegel, D Bartkowiak, D Bottke, C Bronner, U Steiner… - European urology, 2014 - Elsevier
Background Local failure after radical prostatectomy (RP) is common in patients with cancer
extending beyond the capsule. Three prospectively randomized trials demonstrated an …

Benefits and risks of primary treatments for high-risk localized and locally advanced prostate cancer: an international multidisciplinary systematic review

L Moris, MG Cumberbatch, T Van den Broeck… - European urology, 2020 - Elsevier
Context The optimal treatment for men with high-risk localized or locally advanced prostate
cancer (PCa) remains unknown. Objective To perform a systematic review of the existing …

Adjuvant versus early salvage radiation therapy for men at high risk for recurrence following radical prostatectomy for prostate cancer and the risk of death

D Tilki, MH Chen, J Wu, H Huland… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Adjuvant compared with early salvage radiation therapy (sRT) following radical
prostatectomy (RP) has not been shown to reduce progression-free survival in randomized …

Metastasis-directed therapy of regional and distant recurrences after curative treatment of prostate cancer: a systematic review of the literature

P Ost, A Bossi, K Decaestecker, G De Meerleer… - European urology, 2015 - Elsevier
Context The introduction of novel imaging modalities has increased the detection of
oligometastatic prostate cancer (PCa) recurrence, potentially justifying the use of a …

[HTML][HTML] Biomarker detection technologies and future directions

SB Nimse, MD Sonawane, KS Song, T Kim - Analyst, 2016 - pubs.rsc.org
Biomarkers play a vital role in disease detection and treatment follow-up. It is important to
note that diseases in the early stage are typically treated with the greatest probability of …