Background High‐grade serous ovarian carcinoma (HGSOC) is the most common and
aggressive histotype of epithelial ovarian cancer. The heterogeneity and molecular basis of …

A central goal in biology is to determine the ways in which evolution repeats itself. One of the
most remarkable examples in nature of convergent evolutionary novelty is animal venom …

Intensive epigenome and transcriptome analyses have unveiled numerous biological
mechanisms, including the regulation of cell differentiation, proliferation, and induced …

Objective Bazhen Decoction (BZD) is a common adjuvant therapy drug for colorectal cancer
(CRC), although its anti-tumor mechanism is unknown. This study aims to explore the core …

The epidermal growth factor receptor (EGFR) triggers the activation of many intracellular
signals that control cell proliferation, growth, survival, migration, and differentiation. Given its …

Glioblastoma Multiforme (GBM) is an aggressive adult primary brain tumor with poor
prognosis. GBM patients develop resistance to the frontline chemotherapy, temozolomide …

Introduction Peripheral nerve injuries have been associated with increased healthcare costs
and decreased patients' quality of life. Aging represents one factor that slows the speed of …

In cancer, the activating transcription factor 2 (ATF2) has pleiotropic functions in cellular
responses to growth stimuli, damage, or inflammation. Due to only limited studies, the …

p21-activated kinases (PAKs) are serine/threonine protein kinases acting as effectors of
CDC42 and RAC, which are members of the RHO family of small GTPases. PAK1's kinase …

Simple Summary The study discusses the potential of targeting transcription factors (TFs) for
cancer therapy and provide a systematic classification of various types of TFs involved in the …