Cell type-specific expression profiling unravels the development and evolution of stinging cells in sea anemone

K Sunagar, YY Columbus-Shenkar, A Fridrich… - BMC biology, 2018 - Springer
Background Cnidocytes are specialized cells that define the phylum Cnidaria. They possess
an “explosive” organelle called cnidocyst that is important for prey capture and anti-predator …

Modeling of the senescence-associated phenotype in human skin fibroblasts

M Gerasymchuk, GI Robinson, O Kovalchuk… - International journal of …, 2022 - mdpi.com
Modern understanding of aging is based on the accumulation of cellular damage during
one's life span due to the gradual deterioration of regenerative mechanisms in response to …

miR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma

LK Mathew, N Skuli, V Mucaj, SS Lee… - Proceedings of the …, 2014 - National Acad Sciences
Glioblastoma multiforme (GBM) and the mesenchymal GBM subtype in particular are highly
malignant tumors that frequently exhibit regions of severe hypoxia and necrosis. Because …

Essential oil of Foeniculum vulgare subsp. piperitum fruits exerts an anti‑tumor effect in triple‑negative breast cancer cells

M Lauricella, A Maggio… - Molecular …, 2022 - spandidos-publications.com
At present, the growing spread of tumor cases worldwide renders the research of new
promising and selective anticancer drugs urgent. The biological action of extracts of …

Selenotranscriptome network in non-alcoholic fatty liver disease

K Day, LA Seale, RM Graham, BR Cardoso - Frontiers in nutrition, 2021 - frontiersin.org
Observational studies indicate that selenium may contribute to the pathogenesis of non-
alcoholic fatty liver disease (NAFLD). Transcriptomic exploration of the aetiology and …

EGR1 upregulation during encephalitic viral infections contributes to inflammation and cell death

CW Lehman, A Smith, J Kelly, JL Jacobs, JD Dinman… - Viruses, 2022 - mdpi.com
Early growth response 1 (EGR1) is an immediate early gene and transcription factor
previously found to be significantly upregulated in human astrocytoma cells infected with …

Tools for investigating O-GlcNAc in signaling and other fundamental biological pathways

ZM Nelson, GD Leonard, C Fehl - Journal of Biological Chemistry, 2024 - ASBMB
Cells continuously fine-tune signaling pathway proteins to match nutrient and stress levels in
their local environment by modifying intracellular proteins with O-linked N …

Oral administration of Lactobacillus plantarum HY7714 protects hairless mouse against ultraviolet B-induced photoaging

HM Kim, DE Lee, SD Park, YT Kim, YJ Kim… - … of Microbiology and …, 2014 - koreascience.kr
Ultraviolet (UV) irradiation alters multiple molecular pathways in the skin, thereby inducing
skin damage, including photoaging. In recent years, probiotics have gained interest due to …

White spot syndrome virus establishes a novel IE1/JNK/c-Jun positive feedback loop to drive replication

S Wang, H Li, S Weng, C Li, J He - Iscience, 2020 - cell.com
Viruses need to hijack and manipulate host proteins to guarantee their replication. Herein,
we uncovered that the DNA virus white spot syndrome virus (WSSV) established a novel …

[HTML][HTML] Palbociclib inhibits epithelial-mesenchymal transition and metastasis in breast cancer via c-Jun/COX-2 signaling pathway

G Qin, F Xu, T Qin, Q Zheng, D Shi, W Xia, Y Tian… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Palbociclib, a highly selective CDK4/6 inhibitor, has been shown to be a novel anti-tumor
agent that suppresses breast cancer cell proliferation. However, its anti-metastasis activity …