Tissue-resident fibroblasts are mesenchymal cells which possess an impressive plasticity in
their ability to modify their properties according to the requirements of the microenvironment …

The ability of cells to sense and respond to changes in mechanical environment is vital in
conditions of organ injury when the architecture of normal tissues is disturbed or lost. Among …

Fibrogenesis is part of a normal protective response to tissue injury that can become
irreversible and progressive, leading to fatal diseases. Senescent cells are a main driver of …

Cancer remains the leading cause of death around the world. In cancer treatment, over 50%
of cancer patients receive radiotherapy alone or in multimodal combinations with other …

Disruption of the extracellular matrix (ECM) and an accumulation of fibrotic lesions within
tissues are two of the distinctive hallmarks of the aging process. Tissue fibroblasts are …

Tissue-resident fibroblasts are mesenchymal cells which control the structural integrity of the
extracellular matrix (ECM). Fibroblasts possess a remarkable plasticity to allow them to …

This study evaluated the effect of low (20 and 40 mV/mm) intensities of electrical stimulation
on the proliferation and migration of skin fibroblasts from diabetic donors. We also examined …

Insufficient bone fracture repair represents a major clinical and societal burden and novel
strategies are needed to address it. Our data reveal that the transforming growth factor-β …

Abstract Background/Aims As a microvascular complication, diabetic kidney disease is the
leading cause of chronic kidney disease and end‐stage renal disease worldwide. While the …

Senescence is a form of durable cell cycle arrest elicited in response to a wide range of
stimuli. Senescent cells remain metabolically active and secrete a variety of factors …