Molecular mechanism of interaction between SARS-CoV-2 and host cells and interventional therapy

Q Zhang, R Xiang, S Huo, Y Zhou, S Jiang… - Signal transduction and …, 2021 - nature.com
The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …

COVID-19: A promising cure for the global panic

B Vellingiri, K Jayaramayya, M Iyer… - Science of the total …, 2020 - Elsevier
The novel Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, which is the
causative agent of a potentially fatal disease that is of great global public health concern …

Safety and immunogenicity of a recombinant tandem-repeat dimeric RBD-based protein subunit vaccine (ZF2001) against COVID-19 in adults: two randomised …

S Yang, Y Li, L Dai, J Wang, P He, C Li… - The Lancet Infectious …, 2021 - thelancet.com
Background Although several COVID-19 vaccines have been developed so far, they will not
be sufficient to meet the global demand. Development of a wider range of vaccines, with …

[HTML][HTML] Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease

L Fu, F Ye, Y Feng, F Yu, Q Wang, Y Wu, C Zhao… - Nature …, 2020 - nature.com
COVID-19 was declared a pandemic on March 11 by WHO, due to its great threat to global
public health. The coronavirus main protease (M pro, also called 3CLpro) is essential for …

Structural and functional basis of SARS-CoV-2 entry by using human ACE2

Q Wang, Y Zhang, L Wu, S Niu, C Song, Z Zhang, G Lu… - Cell, 2020 - cell.com
The recent emergence of a novel coronavirus (SARS-CoV-2) in China has caused
significant public health concerns. Recently, ACE2 was reported as an entry receptor for …

[HTML][HTML] Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor …

W Tai, L He, X Zhang, J Pu, D Voronin… - Cellular & molecular …, 2020 - nature.com
Abstract The outbreak of Coronavirus Disease 2019 (COVID-19) has posed a serious threat
to global public health, calling for the development of safe and effective prophylactics and …

[HTML][HTML] Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high …

S Xia, M Liu, C Wang, W Xu, Q Lan, S Feng, F Qi, L Bao… - Cell research, 2020 - nature.com
The recent outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 infection in
Wuhan, China has posed a serious threat to global public health. To develop specific anti …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2): a global pandemic and treatment strategies

A Sharma, S Tiwari, MK Deb, JL Marty - International journal of antimicrobial …, 2020 - Elsevier
The emergence and rapid spread of coronavirus disease 2019 (COVID-19), caused by
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a potentially fatal disease …

A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2

R Shi, C Shan, X Duan, Z Chen, P Liu, J Song, T Song… - Nature, 2020 - nature.com
An outbreak of coronavirus disease 2019 (COVID-19),–, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has spread globally. Countermeasures are needed …

Assessment of Iranian nurses' knowledge and anxiety toward COVID-19 during the current outbreak in Iran

M Nemati, B Ebrahimi, F Nemati - Archives of Clinical Infectious …, 2020 - brieflands.com
Background: The world is affected by the Corona Virus Disease 2019 (COVID-19). Because
of their direct contact with patients, health workers, especially nurses, play critical roles in the …