Resurrecting biodiversity: advanced assisted reproductive technologies and biobanking
RL Bolton, A Mooney, MT Pettit… - Reproduction and …, 2022 - raf.bioscientifica.com
Biodiversity is defined as the presence of a variety of living organisms on the Earth that is
essential for human survival. However, anthropogenic activities are causing the sixth mass …
essential for human survival. However, anthropogenic activities are causing the sixth mass …
Improvements in gene editing technology boost its applications in livestock
IV Perisse, Z Fan, GN Singina, KL White… - Frontiers in …, 2021 - frontiersin.org
Accelerated development of novel CRISPR/Cas9-based genome editing techniques
provides a feasible approach to introduce a variety of precise modifications in the …
provides a feasible approach to introduce a variety of precise modifications in the …
Donor-derived spermatogenesis following stem cell transplantation in sterile NANOS2 knockout males
Spermatogonial stem cell transplantation (SSCT) is an experimental technique for transfer of
germline between donor and recipient males that could be used as a tool for biomedical …
germline between donor and recipient males that could be used as a tool for biomedical …
Genome centric engineering using ZFNs, TALENs and CRISPR-Cas9 systems for trait improvement and disease control in Animals
Livestock is an essential life commodity in modern agriculture involving breeding and
maintenance. The farming practices have evolved mainly over the last century for …
maintenance. The farming practices have evolved mainly over the last century for …
CRISPR-based gene drives for pest control
GR McFarlane, CBA Whitelaw, SG Lillico - Trends in biotechnology, 2018 - cell.com
Clustered regularly interspaced short palindromic repeats (CRISPR)-based gene drives
(GDs) could be used to spread desirable genetic elements through wild populations. With …
(GDs) could be used to spread desirable genetic elements through wild populations. With …
Use of gene-editing technology to introduce targeted modifications in pigs
Pigs are an important resource in agriculture and serve as a model for human diseases. Due
to their physiological and anatomical similarities with humans, pigs can recapitulate …
to their physiological and anatomical similarities with humans, pigs can recapitulate …
Livestock gene editing by one-step embryo manipulation
The breakthrough and rapid advance of clustered regularly interspaced short palindromic
repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) technology has enabled the efficient …
repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) technology has enabled the efficient …
On-farm livestock genome editing using cutting edge reproductive technologies
GR McFarlane, HA Salvesen, A Sternberg… - Frontiers in Sustainable …, 2019 - frontiersin.org
The global demand for animal-based food products is anticipated to increase by 70% by
2050. Meeting this demand in a way that has minimal impact on the environment will require …
2050. Meeting this demand in a way that has minimal impact on the environment will require …
Current progress of genome editing in livestock
Historically, genetic engineering in livestock proved to be challenging. Without stable
embryonic stem cell lines to utilize, somatic cell nuclear transfer (SCNT) had to be employed …
embryonic stem cell lines to utilize, somatic cell nuclear transfer (SCNT) had to be employed …
Effects of concentration of CRISPR/Cas9 components on genetic mosaicism in cytoplasmic microinjected porcine embryos
Cytoplasmic microinjection (CI) of the CRISPR/Cas9 system enabled the induction of site-
specific mutations in porcine zygotes and resulting pigs. However, mosaicism is a serious …
specific mutations in porcine zygotes and resulting pigs. However, mosaicism is a serious …