Mesenchymal stem cells for neurological disorders
A Andrzejewska, S Dabrowska, B Lukomska… - Advanced …, 2021 - Wiley Online Library
Neurological disorders are becoming a growing burden as society ages, and there is a
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …
Traumatic brain injury: mechanistic insight on pathophysiology and potential therapeutic targets
Traumatic brain injury (TBI) causes brain damage, which involves primary and secondary
injury mechanisms. Primary injury causes local brain damage, while secondary damage …
injury mechanisms. Primary injury causes local brain damage, while secondary damage …
[HTML][HTML] Emerging role of STING signalling in CNS injury: inflammation, autophagy, necroptosis, ferroptosis and pyroptosis
X Hu, H Zhang, Q Zhang, X Yao, W Ni… - Journal of …, 2022 - Springer
Stimulator of interferons genes (STING), which is crucial for the secretion of type I interferons
and proinflammatory cytokines in response to cytosolic nucleic acids, plays a key role in the …
and proinflammatory cytokines in response to cytosolic nucleic acids, plays a key role in the …
[HTML][HTML] Glucose transporters in brain in health and disease
H Koepsell - Pflügers Archiv-European Journal of Physiology, 2020 - Springer
Energy demand of neurons in brain that is covered by glucose supply from the blood is
ensured by glucose transporters in capillaries and brain cells. In brain, the facilitative …
ensured by glucose transporters in capillaries and brain cells. In brain, the facilitative …
Neuroinflammation: the devil is in the details
There is significant interest in understanding inflammatory responses within the brain and
spinal cord. Inflammatory responses that are centralized within the brain and spinal cord are …
spinal cord. Inflammatory responses that are centralized within the brain and spinal cord are …
[HTML][HTML] Microglial activation in traumatic brain injury
CK Donat, G Scott, SM Gentleman… - Frontiers in aging …, 2017 - frontiersin.org
Microglia have a variety of functions in the brain, including synaptic pruning, CNS repair and
mediating the immune response against peripheral infection. Microglia rapidly become …
mediating the immune response against peripheral infection. Microglia rapidly become …
[HTML][HTML] NLRP3 inflammasome in neurological diseases, from functions to therapies
L Song, L Pei, S Yao, Y Wu, Y Shang - Frontiers in cellular …, 2017 - frontiersin.org
Neuroinflammation has been identified as a causative factor of multiple neurological
diseases. The nucleotide-binding oligomerization domain-, leucine-rich repeat-and pyrin …
diseases. The nucleotide-binding oligomerization domain-, leucine-rich repeat-and pyrin …
[HTML][HTML] Oxidative stress in traumatic brain injury
A Fesharaki-Zadeh - International journal of molecular sciences, 2022 - mdpi.com
Traumatic Brain Injury (TBI) remains a major cause of disability worldwide. It involves a
complex neurometabolic cascade, including oxidative stress. The products of this …
complex neurometabolic cascade, including oxidative stress. The products of this …
Acute management of traumatic brain injury
MA Vella, ML Crandall, MB Patel - Surgical Clinics, 2017 - surgical.theclinics.com
Trauma is the leading cause of death in individuals aged 1 to 45 years, with traumatic brain
injury (TBI) responsible for most these deaths; more than 50,000 deaths per year in the …
injury (TBI) responsible for most these deaths; more than 50,000 deaths per year in the …
Oxidative stress: major threat in traumatic brain injury
Background & Objective: Traumatic Brain Injury (TBI) is one of the major causes of mortality
and morbidity worldwide. It represents mild, moderate and severe effects of physical assault …
and morbidity worldwide. It represents mild, moderate and severe effects of physical assault …