In vivo mapping of cellular resolution neuropathology in brain ischemia with diffusion MRI

D Wu, HH Lee, R Ba, V Turnbill, X Wang, Y Luo… - Science …, 2024 - science.org
Noninvasive mapping of cellular pathology can provide critical diagnostic and prognostic
information. Recent advances in diffusion magnetic resonance imaging enabled in vivo …

Using deep learning to accelerate magnetic resonance measurements of molecular exchange

Z Cheng, S Hu, G Han, K Fang, X Jin… - The Journal of …, 2023 - pubs.aip.org
Real-time monitoring and quantitative measurement of molecular exchange between
different microdomains are useful to characterize the local dynamics in porous media and …

[HTML][HTML] Low-field, high-gradient NMR shows diffusion contrast consistent with localization or motional averaging of water near surfaces

NH Williamson, VJ Witherspoon, TX Cai… - Magnetic Resonance …, 2023 - Elsevier
Nuclear magnetic resonance (NMR) measurements of water diffusion have been extensively
used to probe microstructure in porous materials, such as biological tissue, however …

[HTML][HTML] Molecular localization and exchange kinetics in pharmaceutical liposome and mRNA lipoplex nanoparticle products determined by small angle X-ray …

D Schlattmann, B Weber, L Wyszynski… - European Journal of …, 2024 - Elsevier
We have used pulsed field gradient (PFG)-NMR diffusion experiments, also known as
DOSY, in combination with small angle X-ray scattering measurements to investigate …

Investigating exchange, structural disorder, and restriction in gray matter via water and metabolites diffusivity and kurtosis time-dependence

E Mougel, J Valette, M Palombo - Imaging Neuroscience, 2024 - direct.mit.edu
Water diffusion-weighted MRI is a very powerful tool for probing tissue microstructure, but
disentangling the contribution of compartment-specific structural disorder from cellular …

Comparison of three magnetic resonance imaging measures of brain iron in healthy and cocaine use disorder participants

J Voltin, LM Nunn, Z Watson, ZE Brasher… - NMR in …, 2024 - Wiley Online Library
Several magnetic resonance imaging (MRI) measures for quantifying endogenous nonheme
brain iron have been proposed. These correspond to distinct physical properties with …

Diffusional kurtosis time dependence and the water exchange rate for the multi‐compartment Kärger model

JH Jensen - Magnetic Resonance in Medicine, 2024 - Wiley Online Library
Purpose To demonstrate an analytic formula giving the time dependence of the diffusional
kurtosis for the Kärger model (KM) with an arbitrary number of exchanging compartments …

CAT on MOUSE: Control and automation of temperature for single‐sided NMR instruments such as NMR‐MOUSE

S Mailhiot, O Mankinen, J Li… - Magnetic …, 2024 - Wiley Online Library
Temperature‐dependent experiments are a rapidly growing area of interest for low‐field
NMR. In this work, we present a new device for wide‐range temperature control for single …

[PDF][PDF] Multiexponential analysis of diffusion exchange times reveals a distinct exchange process associated with metabolic activity

TX Cai, N Williamson, R Ravin… - Proceedings of the 32nd …, 2023 - nichd.nih.gov
Contrary to prevailing views, recent work suggests that steady-state water exchange
between the intra-and extracellular space is driven, in part, by active metabolic processes …

Quantifying human gray matter microstructure using neurite exchange imaging (NEXI) and 300 mT/m gradients

Q Uhl, T Pavan, M Molendowska, DK Jones… - Imaging …, 2024 - direct.mit.edu
Biophysical models of diffusion tailored to quantify gray matter microstructure are gathering
increasing interest. The two-compartment Neurite EXchange Imaging (NEXI) model has …