In metastatic breast cancer (MBC), the conventional doxorubicin (DOX) has various
problems due to lack of selectivity with subsequent therapeutic failure and adverse effects …

Clinical reports of limited and treatable cancer metastases, a disease state that exists in a
transitional zone between localized and widespread systemic disease, were noted on …

Breast cancer is the most common cancer in women in almost all countries, including
developing countries. In 2008, 1 380 000 new cases and 458 000 breast cancer deaths …

Importance Management of the primary tumor site in patients with metastatic breast cancer
remains controversial. Objective To evaluate the patterns of receipt of initial breast surgery …

Clinical oncology is advancing toward a more personalized treatment orientation, making
the need to understand the biology of metastasis increasingly acute. Dissecting the complex …

Disseminated metastatic breast cancer needs aggressive treatment due to its reduced
response to anticancer treatment and hence low survival and quality of life. Although in …

Abstract Introduction Circulating tumor cells (CTCs) represent an independent predictor of
outcome in patients with metastatic breast cancer (MBC). We assessed the prognostic …

Over the past decade, there has been an increasing use of radiotherapy (RT) for the
treatment of liver metastases. Most often, ablative doses are delivered to focal liver …

Women with metastatic breast cancer face a wide range of medical, practical, and emotional
challenges that impact their quality of life. Research to date, however, has not focused on …

The Glial cell line-derived neurotrophic Family Ligands (GFL) are soluble neurotrophic
factors that are required for development of multiple human tissues, but which are also …