Stem cells exist as normal cells in embryonic and adult tissues. In recent years, scientists
have spared efforts to determine the role of stem cells in treating many diseases. Stem cells …

In the last few decades, tissue engineering has become one of the most studied medical
fields. Even if bone shows self-remodeling properties, in some cases, due to injuries or …

The therapeutic potential of the dental pulp stem (DSC) cell-derived secretome, consisting of
various biomolecules, is undergoing intense research. Despite promising in vitro and in vivo …

In the oral and maxillofacial region, the treatment of severe bone defects, caused by
fractures, cancers, congenital abnormalities, etc., remains a great challenge. In addition …

Collagen is the most widely distributed protein in human body. Within the field of tissue
engineering and regenerative medical applications, collagen-based biomaterials have been …

Regenerative dentistry is a rapidly evolving field in dentistry, which has been driven by
advancements in biomedical engineering research and the rising treatment expectations …

Designing 3D constructs with appropriate materials and structural frameworks for complex
dental restorative/regenerative procedures has always remained a multi-criteria optimization …

Dental stem cells (DSCs) are mesenchymal stem cell-like populations with self-renewal and
multidifferentiation potential. These cells have been studied in regenerative medicine and …

Dental pulp stem cells (DPSCs) can differentiate into vascular endothelial cells and display
sprouting ability. During this process, DPSC responses to the extracellular …

Background The mandible is a functional bio-organ that supports facial structures and helps
mastication and speaking. Large mandible defects, generally greater than 6-cm segment …