Meta-inflammation and metabolic reprogramming of macrophages in diabetes and obesity: the importance of metabolites

S Russo, M Kwiatkowski, N Govorukhina… - Frontiers in …, 2021 - frontiersin.org
Diabetes mellitus type II and obesity are two important causes of death in modern society.
They are characterized by low-grade chronic inflammation and metabolic dysfunction (meta …

The role of macrophages in the development of acute and chronic inflammatory lung diseases

JW Lee, W Chun, HJ Lee, JH Min, SM Kim, JY Seo… - Cells, 2021 - mdpi.com
Macrophages play an important role in the innate and adaptive immune responses of organ
systems, including the lungs, to particles and pathogens. Cumulative results show that …

Transcriptome-based network analysis reveals a spectrum model of human macrophage activation

J Xue, SV Schmidt, J Sander, A Draffehn, W Krebs… - Immunity, 2014 - cell.com
Macrophage activation is associated with profound transcriptional reprogramming. Although
much progress has been made in the understanding of macrophage activation, polarization …

Biological stability of water-based cutting fluids: progress and application

L Tang, Y Zhang, C Li, Z Zhou, X Nie, Y Chen… - Chinese Journal of …, 2022 - Springer
The application of cutting fluid in the field of engineering manufacturing has a history of
hundreds of years, and it plays a vital role in the processing efficiency and surface quality of …

Epigenetic reprogramming of airway macrophages promotes polarization and inflammation in muco-obstructive lung disease

J Hey, M Paulsen, R Toth, D Weichenhan… - Nature …, 2021 - nature.com
Lung diseases, such as cystic fibrosis and COPD, are characterized by mucus obstruction
and chronic airway inflammation, but their mechanistic link remains poorly understood …

Estrogen accelerates the resolution of inflammation in macrophagic cells

A Villa, N Rizzi, E Vegeto, P Ciana, A Maggi - Scientific reports, 2015 - nature.com
Abstract Although 17β-estradiol (E2) anti-inflammatory activity has been well described, very
little is known about the effects of this hormone on the resolution phase of the inflammatory …

Mitochondrial metabolism mediated macrophage polarization in chronic lung diseases

T Dong, X Chen, H Xu, Y Song, H Wang, Y Gao… - Pharmacology & …, 2022 - Elsevier
As the first line of defence in the lung, alveolar macrophage contributes to maintaining lung
immune homoeostasis. Characterized by the heterogeneity and plasticity, macrophages …

Update on the role of alternatively activated macrophages in asthma

Z Jiang, L Zhu - Journal of asthma and allergy, 2016 - Taylor & Francis
Lung macrophages link innate and adaptive immune responses during allergic airway
inflammatory responses. Alveolar macrophages (AMs) and interstitial macrophages are two …

MMP-9 signaling in the left ventricle following myocardial infarction

RP Iyer, M Jung, ML Lindsey - American Journal of …, 2016 - journals.physiology.org
Following myocardial infarction (MI), the left ventricle (LV) undergoes a series of cardiac
wound healing responses that involve both the stimulation of robust inflammation to clear …

Tumor-associated macrophages and anti-tumor therapies: complex links

C Belgiovine, M D'Incalci, P Allavena… - Cellular and Molecular …, 2016 - Springer
Myeloid cells infiltrating the tumor microenvironment, especially tumor-associated
macrophages (TAMs), are essential providers of cancer-related inflammation, a condition …