Objective: The first 70 years of critical care can be considered a period of “industrial
revolution-like” advancement in terms of progressing the understanding and care of critical …

Helicobacter pylori infections are responsible for tremendous morbidity and mortality
worldwide, leading to efforts to eradicate the organism. However, the effectiveness of …

Background Computerized decision support systems are becoming increasingly prevalent
with advances in data collection and machine learning (ML) algorithms. However, they are …

Objective To assess the variation of effect estimates in the analysis of mortality and length of
stay (LOS) in patients with infections caused by extended-spectrum beta-lactamase (ESBL) …

Severe/MDR Gram-negative infections continue to be important infections due to their
impact on patient outcomes, especially in critically ill and immunocompromised hosts. The …

Bloodstream infections (BSIs) after chemotherapy or hematopoietic stem cell transplantation
(HSCT) are a leading cause of morbidity and mortality. Data on 154 BSIs that occurred in …

Objectives The objective of the study was to estimate how the time elapsed from previous
antibiotic use is associated with antibiotic resistance. Methods Data comprised electronic …

The overuse of antibiotics is exacerbating the antibiotic resistance crisis. Since this problem
is a classic common-goods dilemma, it naturally lends itself to a game-theoretic analysis …

Background Effective treatment of sepsis due to carbapenem-resistant Gram-negative
bacteria (CR-GNB) remains a challenge for clinicians worldwide. In recent years, the …

Multi-drug-resistant organisms (MDROs) have become a global threat to human health. Prior
bed occupancy with MDRO infection/colonization is an exposure factor that is closely …