Artemisia: a promising plant for the treatment of cancer

A Taleghani, SA Emami, Z Tayarani-Najaran - Bioorganic & Medicinal …, 2020 - Elsevier
Due to the promising features of the ancient herbal plant Artemisia, its biologic activity has
been investigated for use in modern medicine. In this regard, Artemisia and its active …

Notch1 in cancer therapy: possible clinical implications and challenges

L Gharaibeh, N Elmadany, K Alwosaibai… - Molecular pharmacology, 2020 - ASPET
The Notch family consists of four highly conserved transmembrane receptors. The release of
the active intracellular domain requires the enzymatic activity of γ-secretase. Notch is …

Antioxidant and Antiproliferation Activities of Lemon Verbena (Aloysia citrodora): An In Vitro and In Vivo Study

HM Rashid, AI Mahmod, FU Afifi, WH Talib - Plants, 2022 - mdpi.com
Aloysia citrodora (Verbenaceae) is traditionally used to treat various diseases, including
bronchitis, insomnia, anxiety, digestive, and heart problems. In this study, this plant's …

Eupatilin: a natural pharmacologically active flavone compound with its wide range applications

B Nageen, I Sarfraz, A Rasul, G Hussain… - Journal of Asian …, 2018 - Taylor & Francis
Abstract Eupatilin (5, 7-dihydroxy-3′, 4′, 6-trimethoxyflavone) is a pharmacologically
active flavone which has been isolated from a variety of medicinal plants. Eupatilin is known …

Effects of flavonoids on cancer, cardiovascular and neurodegenerative diseases: Role of NF-κB signaling pathway

MM Barreca, R Alessandro, C Corrado - International Journal of …, 2023 - mdpi.com
Flavonoids are polyphenolic phytochemical compounds found in many plants, fruits,
vegetables, and leaves. They have a multitude of medicinal applications due to their anti …

Eupatilin improves cilia defects in human CEP290 ciliopathy models

JC Corral-Serrano, PE Sladen, D Ottaviani, OF Rezek… - Cells, 2023 - mdpi.com
The photoreceptor outer segment is a highly specialized primary cilium that is essential for
phototransduction and vision. Biallelic pathogenic variants in the cilia-associated gene …

Novel Application of Eupatilin for Effectively Attenuating Cisplatin‐Induced Auditory Hair Cell Death via Mitochondrial Apoptosis Pathway

X Lu, T Deng, H Dong, J Han, Y Yu… - Oxidative Medicine …, 2022 - Wiley Online Library
Eupatilin (5, 7‐dihydroxy‐3′, 4′, 6‐trimethoxyflavone) is a pharmacologically active
flavone that has been isolated from a variety of medicinal plants and possesses a number of …

Medicinal plants in cancer treatment: contribution of nuclear factor-kappa B (NF-kB) inhibitors

R Das, DK Mehta, M Dhanawat - Mini Reviews in Medicinal …, 2022 - ingentaconnect.com
Nuclear factor-kappa B (NF-ΚB) is one of the principal inducible proteins and a predominant
transcription factor that is known to control gene expression in mammals. It plays a pivotal …

Andrographolide exerts anti-inflammatory effects in Mycobacterium tuberculosis-infected macrophages by regulating the Notch1/Akt/NF-κB axis

W He, J Sun, Q Zhang, Y Li, Y Fu… - Journal of Leucocyte …, 2020 - academic.oup.com
Tuberculosis is a serious public health problem aggravated by the slow progress in the
development of new anti-tuberculosis drugs. The hyper-reactive TB patients have suffered …

Ethnopharmacological properties of Artemisia asiatica: A comprehensive review

A Ahuja, YS Yi, MY Kim, JY Cho - Journal of Ethnopharmacology, 2018 - Elsevier
Abstract Ethnopharmacological relevance Artemisia asiatica Nakai (Compositae) has a long
history as a traditional remedy. Preparation from various parts of the plant (aerial parts and …