During stress, bacteria undergo extensive physiological transformations, many of which are
coordinated by ppGpp. Although ppGpp is best known for enhancing cellular resilience by …

Gene expression occurs in two essential steps: transcription and translation. In bacteria, the
two processes are tightly coupled in time and space, and highly regulated. Tight regulation …

Bacterial enhancer binding proteins (bEBPs) are transcriptional activators that assemble as
hexameric rings in their active forms and utilize ATP hydrolysis to remodel the conformation …

Alternative bacterial sigma factors bind the catalytic core RNA polymerase to confer
promoter selectivity on the holoenzyme. The different holoenzymes are thus programmed to …

Plantaricin LPL-1, produced by Lactobacillus plantarum LPL-1, is a novel class IIa
bacteriocin with bactericidal activity against foodborne bacteria. The aim of this present …

DNA–protein interactions are central to fundamental cellular processes, yet widely
implemented technologies for measuring these interactions on a genome scale in bacteria …

Background Sigma-54 is a central regulator in many pathogenic bacteria and has been
linked to a multitude of cellular processes like nitrogen assimilation and important functional …

It is useful for whole-cell biosensors to be based on colorimetric detection because the
output signal can be easily visualized. However, colorimetric-based whole-cell biosensors …

Nucleoid-associated proteins typically are abundant, low-molecular-mass polypeptides that
bind DNA and alter its shape and its ability to participate in transactions such as …

Biofilms help bacteria survive under adverse conditions, and the quorum sensing (QS)
system plays an important role in regulating their activities. Quorum sensing inhibitors (QSIs) …