Red Light‐Triggered Anti‐Angiogenic and Photodynamic Combination Therapy of Age‐Related Macular Degeneration
S Xu, K Cui, K Long, J Li, N Fan, WC Lam… - Advanced …, 2023 - Wiley Online Library
Choroidal neovascularization (CNV) is the key pathological event of wet age‐related
macular degeneration (wAMD) leading to irreversible vision loss. Currently, anti‐angiogenic …
macular degeneration (wAMD) leading to irreversible vision loss. Currently, anti‐angiogenic …
[HTML][HTML] Ultrasound-induced drug release from stimuli-responsive hydrogels
TJ Yeingst, JH Arrizabalaga, DJ Hayes - Gels, 2022 - mdpi.com
Stimuli-responsive hydrogel drug delivery systems are designed to release a payload when
prompted by an external stimulus. These platforms have become prominent in the field of …
prompted by an external stimulus. These platforms have become prominent in the field of …
Calcium peroxide nanoparticles induce endoplasmic reticulum stress for enhanced radiation therapy of osteosarcoma
Radiation therapy (RT) has been widely used in clinics. The expression of various radiation-
resistant proteins limits the curative effect of RT. Endoplasmic reticulum (ER) plays a critical …
resistant proteins limits the curative effect of RT. Endoplasmic reticulum (ER) plays a critical …
Amino Acid‐Starved Cancer Cells Utilize Macropinocytosis and Ubiquitin‐Proteasome System for Nutrient Acquisition
To grow in nutrient‐deprived tumor microenvironment, cancer cells often internalize and
degrade extracellular proteins to refuel intracellular amino acids. However, the nutrient …
degrade extracellular proteins to refuel intracellular amino acids. However, the nutrient …
Tailoring drug delivery systems by microfluidics for tumor therapy
Q Zhang, G Kuang, L Wang, L Fan, Y Zhao - Materials Today, 2024 - Elsevier
Drug delivery systems (DDSs) for tumor treatment is a specialized method aimed at
transporting therapeutic substances, especially anticancer drugs, to specific target areas in …
transporting therapeutic substances, especially anticancer drugs, to specific target areas in …
Identification of a Sonically Activated Degrader of Methionine Adenosyltransferase 2A by an in Silico Approach Assisted with the Hole–Electron Analysis
H He, Z Wang, X Peng, L Qing, Y Zhang… - Journal of Medicinal …, 2024 - ACS Publications
Small molecules capable of modulating methionine adenosyltransferase 2A (MAT2A) are of
significant interest in precise cancer therapeutics. Herein, we raised the hole–electron …
significant interest in precise cancer therapeutics. Herein, we raised the hole–electron …
[HTML][HTML] Cerium oxide-based nanozyme suppresses kidney calcium oxalate crystal depositions via reversing hyperoxaluria-induced oxidative stress damage
J Deng, B Yu, Z Chang, S Wu, G Li, W Chen… - Journal of …, 2022 - Springer
Oxidative stress damage to renal epithelial cells is the main pathological factor of calcium
oxalate calculi formation. The development of medicine that could alleviate oxidative …
oxalate calculi formation. The development of medicine that could alleviate oxidative …
Nanoplatform‐based in vivo gene delivery systems for cancer therapy
R Luo, H Le, Q Wu, C Gong - Small, 2024 - Wiley Online Library
Gene therapy uses modern molecular biology methods to repair disease‐causing genes. As
a burgeoning therapeutic, it has been widely applied for cancer therapy. Since 1989, there …
a burgeoning therapeutic, it has been widely applied for cancer therapy. Since 1989, there …
Boosting the immunoactivity of T cells by resonant thermal radiation from electric graphene films for improved cancer immunotherapy
To investigate the effect of resonant thermal radiation from electric graphene films (GFs) to
the immunoactivity of T cells in situ and the benefits to cancer immunotherapy. This work …
the immunoactivity of T cells in situ and the benefits to cancer immunotherapy. This work …
Ultrasound nanomedicine and materdicine
Z Wang, X Wang, M Chang, J Guo… - Journal of Materials …, 2023 - pubs.rsc.org
The conventional microbubble-based ultrasound biomedicine clinically plays a vital role in
providing the dynamic detection of macro and microvasculature and disease theranostics …
providing the dynamic detection of macro and microvasculature and disease theranostics …