Spinal cord regeneration

W Young - Cell transplantation, 2014 - journals.sagepub.com
Three theories of regeneration dominate neuroscience today, all purporting to explain why
the adult central nervous system (CNS) cannot regenerate. One theory proposes that Nogo …

Cell therapy for spinal cord regeneration

SM Willerth, SE Sakiyama-Elbert - Advanced drug delivery reviews, 2008 - Elsevier
This review presents a summary of the various types of cellular therapy used to treat spinal
cord injury. The inhibitory environment and loss of axonal connections after spinal cord …

[HTML][HTML] Promotion of remyelination by adipose mesenchymal stem cell transplantation in a cuprizone model of multiple sclerosis

A Hedayatpour, I Ragerdi, P Pasbakhsh… - Cell Journal …, 2013 - ncbi.nlm.nih.gov
Objective: Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the
central nervous system (CNS). Stem cell transplantation is a new therapeutic approach for …

[HTML][HTML] Ischemic preconditioning protects against spinal cord ischemia-reperfusion injury in rabbits by attenuating blood spinal cord barrier disruption

B Fang, XM Li, XJ Sun, NR Bao, XY Ren… - International Journal of …, 2013 - mdpi.com
Ischemic preconditioning has been reported to protect against spinal cord ischemia-
reperfusion (IR) injury, but the underlying mechanisms are not fully understood. To …

[HTML][HTML] Dopamine regulates mobilization of mesenchymal stem cells during wound angiogenesis

S Shome, PS Dasgupta, S Basu - PLoS One, 2012 - journals.plos.org
Angiogenesis is an important step in the complex biological and molecular events leading to
successful healing of dermal wounds. Among the different cellular effectors of wound …

[HTML][HTML] Intrathecal transplantation of bone marrow stromal cells attenuates blood-spinal cord barrier disruption induced by spinal cord ischemia-reperfusion injury in …

B Fang, H Wang, XJ Sun, XQ Li, CY Ai, WF Tan… - Journal of vascular …, 2013 - Elsevier
Objective Intrathecal administration of bone marrow stromal cells has been found to produce
beneficial effects on ischemia-reperfusion injury to the spinal cord. The blood-spinal cord …

Intraspinal cord graft of autologous activated Schwann cells efficiently promotes axonal regeneration and functional recovery after rat's spinal cord injury

DX Ban, XH Kong, SQ Feng, GZ Ning, JT Chen… - Brain Research, 2009 - Elsevier
Basic research in spinal cord injury (SCI) has made great strides in recent years, and some
new insights and strategies have been applied in promoting effective axonal regrowth and …

[HTML][HTML] Hypoxic preconditioning increases the protective effect of bone marrow mesenchymal stem cells on spinal cord ischemia/reperfusion injury

Z Wang, BO Fang, Z Tan… - Molecular Medicine …, 2016 - spandidos-publications.com
Transplantation of bone marrow mesenchymal stem cells (BMSCs) protect against spinal
cord ischemia/reperfusion injury (SCIRI). However, a large number of transplanted BMSCs …

Therapeutic Effects of Intravenous Injection of Fresh and Frozen Thawed HO‐1‐Overexpressed Ad‐MSCs in Dogs with Acute Spinal Cord Injury

IU Khan, Y Yoon, KU Choi, KR Jo, N Kim… - Stem Cells …, 2019 - Wiley Online Library
Owing to the antioxidant and anti‐inflammatory functions of hemeoxygenase‐1 (HO‐1), HO‐
1‐expressing canine adipose‐derived mesenchymal stem cells (Ad‐MSCs) could be …

[HTML][HTML] Pluripotent stem cells-a review of the current status in neural regeneration

SAB Paspala, T Murthy, VS Mahaboob… - Neurology …, 2011 - journals.lww.com
Pharmacological or neurosurgical therapies currently in practice to treat the damage in
various neurodegenerative disorders are not efficient in preventing progression or cure of …