Sialylated glycan bindings from SARS-CoV-2 spike protein to blood and endothelial cells govern the severe morbidities of COVID-19
DE Scheim, P Vottero, AD Santin, AG Hirsh - International journal of …, 2023 - mdpi.com
Consistent with well-established biochemical properties of coronaviruses, sialylated glycan
attachments between SARS-CoV-2 spike protein (SP) and host cells are key to the virus's …
attachments between SARS-CoV-2 spike protein (SP) and host cells are key to the virus's …
N1-methyl-pseudouridine (m1Ψ): Friend or foe of cancer?
A Rubio-Casillas, D Cowley, M Raszek… - International Journal of …, 2024 - Elsevier
Due to the health emergency created by SARS-CoV-2, the virus that causes the COVID-19
disease, the rapid implementation of a new vaccine technology was necessary. mRNA …
disease, the rapid implementation of a new vaccine technology was necessary. mRNA …
COVID-19 vaccines and myocardial injury
DA Bluemke - Radiology, 2023 - pubs.rsna.org
The development of messenger RNA (mRNA) COVID-19 vaccines is a remarkable biotech
story. While traditional vaccines took 5-10 years to develop, the COVID-19 vaccines took …
story. While traditional vaccines took 5-10 years to develop, the COVID-19 vaccines took …
The mRNA-LNP vaccines–the good, the bad and the ugly?
BZ Igyártó, Z Qin - Frontiers in Immunology, 2024 - frontiersin.org
The mRNA-LNP vaccine has received much attention during the COVID-19 pandemic since
it served as the basis of the most widely used SARS-CoV-2 vaccines in Western countries …
it served as the basis of the most widely used SARS-CoV-2 vaccines in Western countries …
mRNA-LNP COVID-19 Vaccine Lipids Induce Complement Activation and Production of Proinflammatory Cytokines: Mechanisms, Effects of Complement Inhibitors …
T Bakos, T Mészáros, GT Kozma, P Berényi… - International Journal of …, 2024 - mdpi.com
A small fraction of people vaccinated with mRNA–lipid nanoparticle (mRNA-LNP)-based
COVID-19 vaccines display acute or subacute inflammatory symptoms whose mechanism …
COVID-19 vaccines display acute or subacute inflammatory symptoms whose mechanism …
[HTML][HTML] Post-COVID-19 vaccination myocarditis: a prospective cohort study pre and post vaccination using cardiovascular magnetic resonance
Background Concerns about COVID-19 vaccination induced myocarditis or subclinical
myocarditis persists in some populations. Cardiac magnetic resonance imaging (CMR) has …
myocarditis persists in some populations. Cardiac magnetic resonance imaging (CMR) has …
[HTML][HTML] Application of Advanced Bioimaging Technologies in Viral Infections
Y Sun, C Cao, Y Peng, X Dai, X Li, J Li, T Liang… - Materials Today …, 2024 - Elsevier
Viruses are major pathogens responsible for a wide range of infectious diseases that may
lead to global pandemics. The understanding of structural underpinnings of virions …
lead to global pandemics. The understanding of structural underpinnings of virions …
A Focus on the Pathophysiology of Adrenomedullin Expression: Endothelitis and Organ Damage in Severe Viral and Bacterial Infections
Adrenomedullin (ADM) is a peptide hormone produced primarily in the adrenal glands,
playing a crucial role in various physiological processes. As well as improving vascular …
playing a crucial role in various physiological processes. As well as improving vascular …
Long‐lasting, biochemically modified mRNA, and its frameshifted recombinant spike proteins in human tissues and circulation after COVID‐19 vaccination
LG Boros, AM Kyriakopoulos, C Brogna… - Pharmacology …, 2024 - Wiley Online Library
According to the CDC, both Pfizer and Moderna COVID‐19 vaccines contain nucleoside‐
modified messenger RNA (mRNA) encoding the viral spike glycoprotein of severe acute …
modified messenger RNA (mRNA) encoding the viral spike glycoprotein of severe acute …
Back to the Basics of SARS-CoV-2 Biochemistry: Microvascular Occlusive Glycan Bindings Govern Its Morbidities and Inform Therapeutic Responses
Consistent with the biochemistry of coronaviruses as well established over decades, SARS-
CoV-2 makes its initial attachment to host cells through the binding of its spike protein (SP) …
CoV-2 makes its initial attachment to host cells through the binding of its spike protein (SP) …