Biomarker development in the precision medicine era: lung cancer as a case study

AJ Vargas, CC Harris - Nature reviews cancer, 2016 - nature.com
Precision medicine relies on validated biomarkers with which to better classify patients by
their probable disease risk, prognosis and/or response to treatment. Although …

[HTML][HTML] [18F] FDG-PET/CT radiomics and artificial intelligence in lung cancer: Technical aspects and potential clinical applications

R Manafi-Farid, E Askari, I Shiri, C Pirich… - Seminars in nuclear …, 2022 - Elsevier
Lung cancer is the second most common cancer and the leading cause of cancer-related
death worldwide. Molecular imaging using [18 F] fluorodeoxyglucose Positron Emission …

[HTML][HTML] Imaging phenotyping using radiomics to predict micropapillary pattern within lung adenocarcinoma

SH Song, H Park, G Lee, HY Lee, I Sohn… - Journal of Thoracic …, 2017 - Elsevier
Abstract Introduction Lung adenocarcinomas (ADCs) with a micropapillary pattern have
been reported to have a poor prognosis. However, few studies have reported on the imaging …

[HTML][HTML] Primary invasive mucinous adenocarcinoma of the lung: prognostic value of CT imaging features combined with clinical factors

T Wang, Y Yang, X Liu, J Deng, J Wu… - Korean Journal of …, 2021 - ncbi.nlm.nih.gov
Objective To investigate the association between CT imaging features and survival
outcomes in patients with primary invasive mucinous adenocarcinoma (IMA). Materials and …

Importance of CT image normalization in radiomics analysis: prediction of 3-year recurrence-free survival in non-small cell lung cancer

D Park, D Oh, MH Lee, SY Lee, KM Shin, JSG Jun… - European …, 2022 - Springer
Objectives To analyze whether CT image normalization can improve 3-year recurrence-free
survival (RFS) prediction performance in patients with non-small cell lung cancer (NSCLC) …

[PDF][PDF] Role of PET/CT in management of early lung adenocarcinoma

X Shao, R Niu, Z Jiang, X Shao… - American Journal of …, 2020 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study was to explore the value of FDG PET combined with
high-resolution CT (HRCT) in predicting the pathologic subtypes and growth patterns of …

[HTML][HTML] Radiomics nomogram for prediction disease-free survival and adjuvant chemotherapy benefits in patients with resected stage I lung adenocarcinoma

D Xie, TT Wang, SJ Huang, JJ Deng… - Translational Lung …, 2020 - ncbi.nlm.nih.gov
Background Robust imaging biomarkers are needed for risk stratification in stage I lung
adenocarcinoma patients in order to select optimal treatment regimen. We aimed to …

Prediction of micropapillary and solid pattern in lung adenocarcinoma using radiomic values extracted from near-pure histopathological subtypes

LW Chen, SM Yang, HJ Wang, YC Chen, MW Lin… - European …, 2021 - Springer
Objectives Near-pure lung adenocarcinoma (ADC) subtypes demonstrate strong
stratification of radiomic values, providing basic information for pathological subtyping. We …

Procedure-specific risk prediction for recurrence in patients undergoing lobectomy or sublobar resection for small (≤ 2 cm) lung adenocarcinoma: an international …

S Bains, T Eguchi, A Warth, YC Yeh, J Nitadori… - Journal of Thoracic …, 2019 - Elsevier
Introduction This work was performed to develop and validate procedure-specific risk
prediction for recurrence following resection for early-stage lung adenocarcinoma (ADC) …

Radiomics is feasible for prediction of spread through air spaces in patients with nonsmall cell lung cancer

Y Onozato, T Nakajima, H Yokota, J Morimoto… - Scientific Reports, 2021 - nature.com
Tumor spread through air spaces (STAS) in non-small-cell lung cancer (NSCLC) is known to
influence a poor patient outcome, even in patients presenting with early-stage disease …