Feedback from oestradiol (E2) plays a critical role in the regulation of major events in the
physiological menstrual cycle including the release of gonadotrophins to stimulate follicular …

The mechanism by which arcuate nucleus kisspeptin (ARN KISS) neurons co-expressing
glutamate, neurokinin B, and dynorphin intermittently synchronize their activity to generate …

Technical innovation in neuroscience introduced powerful tools for measuring and
manipulating neuronal activity via optical, chemogenetic, and calcium-imaging tools. These …

Obesity is associated with hypogonadism in males, characterized by low testosterone and
sperm number. Previous studies determined that these stem from dysregulation of …

The obligatory role of kisspeptin (KISS1) and its receptor (KISS1R) in regulating the
hypothalamic-pituitary–gonadal axis, puberty and fertility was uncovered in 2003. In the few …

This paper is the forty-fourth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

There is considerable evidence that synchronized activity within a reciprocally connected
population of cells in the arcuate nucleus (ARC) coexpressing kisspeptin, neurokinin B …

A major obstacle to monitoring pulsatile luteinizing hormone (LH) secretion in mice has
been an assay with sufficient sensitivity in small blood volumes. In 2013, Steyn and …

Kisspeptin neurons in the arcuate nucleus of the hypothalamus generate gonadotrophin‐
releasing hormone (GnRH) pulses, and act as critical initiators of functional gonadotrophin …

Kisspeptin neurons are mainly located in the arcuate (Kiss1ARC, vis-à-vis the GnRH pulse
generator) and anteroventral periventricular nucleus (Kiss1AVPV, vis-à-vis the GnRH surge …