Ochratoxin A: molecular interactions, mechanisms of toxicity and prevention at the molecular level

T Kőszegi, M Poór - Toxins, 2016 - mdpi.com
Ochratoxin A (OTA) is a widely-spread mycotoxin all over the world causing major health
risks. The focus of the present review is on the molecular and cellular interactions of OTA. In …

Citrus flavonoids and their antioxidant evaluation

Y Wang, XJ Liu, JB Chen, JP Cao, X Li… - Critical Reviews in …, 2022 - Taylor & Francis
The antioxidant ability is the link and bridge connecting a variety of biological activities.
Citrus flavonoids play an essential role in regulating oxidative stress and are an important …

Risk assessment of ochratoxin A in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
Abstract The European Commission asked EFSA to update their 2006 opinion on ochratoxin
A (OTA) in food. OTA is produced by fungi of the genus Aspergillus and Penicillium and …

Metabolism and pharmacological activities of the natural health-benefiting compound diosmin

Y Zheng, R Zhang, W Shi, L Li, H Liu, Z Chen, L Wu - Food & function, 2020 - pubs.rsc.org
Diosmin is a famous natural flavonoid for treating chronic venous insufficiency and varicose
veins. Recently, extensive study has indicated that diosmin possesses diverse …

Ochratoxin A-induced nephrotoxicity: Up-to-date evidence

CS Khoi, JH Chen, TY Lin, CK Chiang… - International journal of …, 2021 - mdpi.com
Ochratoxin A (OTA) is a mycotoxin widely found in various foods and feeds that have a
deleterious effect on humans and animals. It has been shown that OTA causes multiorgan …

Intracellular antioxidant detoxifying effects of diosmetin on 2, 2-azobis (2-amidinopropane) dihydrochloride (AAPH)-induced oxidative stress through inhibition of …

W Liao, Z Ning, L Chen, Q Wei, E Yuan… - Journal of agricultural …, 2014 - ACS Publications
The intracellular antioxidant activities of diosmetin were evaluated by cellular antioxidant
activity (CAA) assay, 2, 2-azobis (2-amidinopropane) dihydrochloride (AAPH)-induced …

Xenobiotic transporters and kidney injury

B George, D You, MS Joy, LM Aleksunes - Advanced drug delivery reviews, 2017 - Elsevier
Renal proximal tubules are targets for toxicity due in part to the expression of transporters
that mediate the secretion and reabsorption of xenobiotics. Alterations in transporter …

Effects of curcumin on performance, antioxidation, intestinal barrier and mitochondrial function in ducks fed corn contaminated with ochratoxin A

D Ruan, WC Wang, CX Lin, AM Fouad, W Chen… - Animal, 2019 - cambridge.org
Curcumin has been attributed with antioxidant, anti-inflammatory, antibacterial activities, and
has shown highly protective effects against enteropathogenic bacteria and mycotoxins …

Natural products for the immunotherapy of glioma

Q Huang, X Pan, W Zhu, W Zhao, H Xu, K Hu - Nutrients, 2023 - mdpi.com
Glioma immunotherapy has attracted increasing attention since the immune system plays a
vital role in suppressing tumor growth. Immunotherapy strategies are already being tested in …

Ochratoxin A–induced genotoxic and epigenetic mechanisms lead to Alzheimer disease: its modulation with strategies

K Niaz, SZA Shah, F Khan, M Bule - Environmental Science and Pollution …, 2020 - Springer
Ochratoxin A (OTA) is a naturally occurring mycotoxin mostly found in food items including
grains and coffee beans. It induces DNA single-strand breaks and has been considered to …