The structure-antifungal activity relationship of 5, 7-dihydroxyflavonoids against Penicillium italicum

S Yang, J Zhou, D Li, C Shang, L Peng, S Pan - Food chemistry, 2017 - Elsevier
To evaluate the structure-activity relationship of 5, 7-dihydroxyflavonoids against P. italicum,
we tested the antifungal activity of 23 selected 5, 7-dihydroxyflavonoids against spore …

Inhibition of TGF-β Signaling in Gliomas by the Flavonoid Diosmetin Isolated from Dracocephalum peregrinum L.

Y Yan, X Liu, J Gao, Y Wu, Y Li - Molecules, 2020 - mdpi.com
Background: Dracocephalum peregrinum L., a traditional Kazakh medicine, has good
expectorant, anti-cough, and to some degree, anti-asthmatic effects. Diosmetin (3′, 5, 7 …

Ochratoxin A activates neutrophils and kills these cells through necrosis, an effect eliminated through its conversion into ochratoxin α

L Kupski, M Freitas, D Ribeiro, EB Furlong… - Toxicology, 2016 - Elsevier
Ochratoxin A (OTA) is a mycotoxin produced by several species of fungi from the Aspergillus
and Penicillium genera that frequently grow in improperly stored food products. OTA has …

Bacteria pyruvate metabolism modulates AFB1 toxicity in Caenorhabditis elegans

B Tang, KS Xue, JS Wang, PL Williams… - Science of The Total …, 2023 - Elsevier
Abstract Aflatoxin B 1 (AFB 1), the most potent mycotoxin and Group 1 human carcinogen,
continues to pose a significant public health burden, particularly in developing countries …

[HTML][HTML] Diosmetin protects against retinal injury via reduction of DNA damage and oxidative stress

Z Shen, J Shao, J Dai, Y Lin, X Yang, J Ma, Q He… - Toxicology Reports, 2016 - Elsevier
Visual impairment is a global public health problem that needs new candidate drugs.
Chrysanthemum is a traditional Chinese drug, famous for its eye-protective function, with an …

Complex formation of flavonoids fisetin and geraldol with β-cyclodextrins

N Sali, R Csepregi, T Kőszegi, S Kunsági-Máté… - Journal of …, 2018 - Elsevier
Fisetin (FIS) is a flavonoid aglycone which is widely distributed in several fruits and
vegetables. Based on its complex biochemical action in the body, FIS seems a promising …

Determination of Metabolites of Diosmetin-7-O-glucoside by a Newly Isolated Escherichia coli from Human Gut Using UPLC-Q-TOF/MS

M Zhao, L Du, J Tao, D Qian, E Shang… - Journal of agricultural …, 2014 - ACS Publications
Different human intestinal bacteria were isolated and screened for their ability to transform
diosmetin-7-O-glucoside. A Gram-negative anaerobic bacterium, strain 4, capable of …

Diosmetin as a promising natural therapeutic agent: In vivo, in vitro mechanisms, and clinical studies

Z Sun, K Liu, C Liang, L Wen, J Wu… - Phytotherapy …, 2024 - Wiley Online Library
Diosmetin, a natural occurring flavonoid, is primarily found in citrus fruits, beans, and other
plants. Diosmetin demonstrates a variety of pharmacological activities, including anticancer …

Regioselective glucuronidation of diosmetin and chrysoeriol by the interplay of glucuronidation and transport in UGT1A9-Overexpressing hela cells

X Zeng, J Shi, M Zhao, Q Chen, L Wang, H Jiang… - PLoS …, 2016 - journals.plos.org
This study aimed to determine the reaction kinetics of the regioselective glucuronidation of
diosmetin and chrysoeriol, two important methylated metabolites of luteolin, by human liver …

Novel effect of Daflon and low-dose γ-radiation in modulation of thioacetamide-induced hepatic encephalopathy in male albino rats

MK Abdel-Rafei, MM Amin… - Human & experimental …, 2017 - journals.sagepub.com
This study was designed to evaluate the hepato and neuroprotective activity of Daflon and
low-dose γ radiation on thioacetamide (TAA)-induced liver damage and hepatic …