Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena

LV Lima, TSS Abner, KA Sluka - The Journal of physiology, 2017 - Wiley Online Library
Exercise is an integral part of the rehabilitation of patients suffering a variety of chronic
musculoskeletal conditions, such as fibromyalgia, chronic low back pain and myofascial …

[HTML][HTML] Endogenous systems involved in exercise-induced analgesia.

RDS Santos, G Galdino - JPP, 2018 - jpp.krakow.pl
Exercise-induced analgesia is a phenomenon discussed worldwide. This effect began to be
investigated in the early 1970s in healthy individuals and rodents during and after an acute …

Opioid receptors and cardioprotection–'opioidergic conditioning'of the heart

JP Headrick, LE See Hoe, EF Du Toit… - British journal of …, 2015 - Wiley Online Library
Ischaemic heart disease (IHD) remains a major cause of morbidity/mortality globally, firmly
established in W esternized or 'developed'countries and rising in prevalence in developing …

[HTML][HTML] Mechanism of exercise-induced analgesia: what we can learn from physically active animals

JB Lesnak, KA Sluka - Pain Reports, 2020 - journals.lww.com
Physical activity has become a first-line treatment in rehabilitation settings for individuals
with chronic pain. However, research has only recently begun to elucidate the mechanisms …

Blood flow restriction induces hypoalgesia in recreationally active adult male anterior knee pain patients allowing therapeutic exercise loading

V Korakakis, R Whiteley, K Epameinontidis - Physical Therapy in Sport, 2018 - Elsevier
Objective To evaluate if a single blood flow restriction (BFR)-exercise bout would induce
hypoalgaesia in patients with anterior knee pain (AKP) and allow painless application of …

[HTML][HTML] Emerging relationships between exercise, sensory nerves, and neuropathic pain

MA Cooper, PM Kluding, DE Wright - Frontiers in neuroscience, 2016 - frontiersin.org
The utilization of physical activity as a therapeutic tool is rapidly growing in the medical
community and the role exercise may offer in the alleviation of painful disease states is an …

[HTML][HTML] Regular physical activity prevents development of chronic muscle pain through modulation of supraspinal opioid and serotonergic mechanisms

RG Brito, LA Rasmussen, KA Sluka - Pain reports, 2017 - journals.lww.com
Objectives: The purpose was to examine central inhibitory mechanisms involved in
analgesia produced by wheel running. Methods: C57/Black6 mice were given access to …

Effects of activity-dependent strategies on regeneration and plasticity after peripheral nerve injuries

E Udina, S Cobianchi, I Allodi, X Navarro - Annals of Anatomy …, 2011 - Elsevier
Peripheral nerve injuries result in loss of motor, sensory and autonomic functions of the
denervated limb, but are also accompanied by positive symptoms, such as hyperreflexia …

Mechanisms of placebo analgesia: a dual-process model informed by insights from cross-species comparisons

SM Schafer, S Geuter, TD Wager - Progress in neurobiology, 2018 - Elsevier
Placebo treatments are pharmacologically inert, but are known to alleviate symptoms across
a variety of clinical conditions. Associative learning and cognitive expectations both play …

Acute resistance exercise induces antinociception by activation of the endocannabinoid system in rats

G Galdino, T Romero, JFP da Silva… - Anesthesia & …, 2014 - journals.lww.com
BACKGROUND: Resistance exercise (RE) is also known as strength training, and it is
performed to increase the strength and mass of muscles, bone strength, and metabolism. RE …