SUMMARY ME/CFS is a serious and poorly understood disease. To understand immune
dysregulation in ME/CFS, we used single-cell RNA-seq (scRNA-seq) to examine immune …

Defective ribosome biogenesis (RiBi) underlies a group of clinically diverse human diseases
collectively known as the ribosomopathies, core manifestations of which include cytopenias …

Cell diversification is at the base of increasing multicellular organism complexity in
phylogeny achieved during ontogeny. However, there are also functions common to all cells …

Simple Summary This study identifies specific ribosomal proteins that drive MBM and
extracranial metastasis via CTCs. Dual targeting of cellular translation and proliferation …

Background: Mutant KRAS-induced tumorigenesis is prevalent in the lung, colon, and
pancreatic ductal adenocarcinomas. For the past 3 decades, KRAS mutants seem …

Diamond-Blackfan anemia (DBA) is a rare congenital bone marrow failure disorder
characterized by erythroid hypoplasia. It primarily affects infants and is often caused by …

The term moonlighting proteins refers to those proteins that present alternative functions
performed by a single polypeptide chain acquired throughout evolution (called canonical …

Martynoside (MAR), a bioactive component in several well-known tonic traditional Chinese
herbs, exhibits pro-hematopoietic activity during 5-fluorouracil (5-FU) treatment. However …

Amino acid availability is crucial for cancer cells' survivability. Leukemia and colorectal
cancer cells have been shown to resist asparagine depletion by utilizing GSK3-dependent …

For over two decades, Rituximab and CHOP combination treatment (rCHOP) has remained
the standard treatment approach for diffuse large B-cell lymphoma (DLBCL). Despite …