Telomeres are nucleoprotein structures that play a pivotal role in the protection and
maintenance of eukaryotic chromosomes. Telomeres and the enzyme telomerase, which …

Cell diversification is at the base of increasing multicellular organism complexity in
phylogeny achieved during ontogeny. However, there are also functions common to all cells …

Background Effectively predicting the risk of adverse pregnancy outcome (APO) in women
with systemic lupus erythematosus (SLE) during early and mid-pregnancy is a challenge …

Enhanced ribosome biogenesis and protein synthesis are required for cell proliferation.
During hematopoietic regeneration, hematopoietic stem cells (HSCs) proliferate rapidly to …

The traditional perception of ribosomes as uniform molecular machines has been
revolutionized by recent discoveries, revealing a complex landscape of ribosomal …

Ribosomal proteins (RPs), the constituents of the ribosome, belong to the most abundant
proteins in the cell. A highly coordinated network of interactions implicating RPs and …

Martynoside (MAR), a bioactive component in several well-known tonic traditional Chinese
herbs, exhibits pro-hematopoietic activity during 5-fluorouracil (5-FU) treatment. However …

Background Mutant KRAS-induced tumorigenesis is prevalent in lung, colon, and pancreatic
ductal adenocarcinomas. For the past 3 decades, KRAS mutants seem undruggable due to …

Rationale: Myocardial infarction (MI) is a severe global clinical condition with widespread
prevalence. The adult mammalian heart's limited capacity to generate new cardiomyocytes …

Simple Summary Ribosomes are macromolecular complexes responsible for mRNA
translation. When ribosome biogenesis is hyperactive or aberrant or ribosomal factors are …