P53: A key player in diverse cellular processes including nuclear stress and ribosome biogenesis, highlighting potential therapeutic compounds
The tumor suppressor proteins are key transcription factors involved in the regulation of
various cellular processes, such as apoptosis, DNA repair, cell cycle, senescence, and …
various cellular processes, such as apoptosis, DNA repair, cell cycle, senescence, and …
Transcriptome Profiling Revealed Basis for Growth Heterosis in Hybrid Tilapia (Oreochromis niloticus ♀ × O. aureus ♂)
J Zhu, Z Zou, D Li, W Xiao, J Yu, B Chen, L Xue… - Fishes, 2022 - mdpi.com
Hybrid tilapia were produced from hybridization of Nile tilapia (Oreochromis niloticus) and
blue tilapia (O. aureus). Comparative transcriptome analysis was carried out on the liver of …
blue tilapia (O. aureus). Comparative transcriptome analysis was carried out on the liver of …
[HTML][HTML] Inhibition of TAF1B impairs ribosome biosynthesis and suppresses cell proliferation in stomach adenocarcinoma through promoting c-MYC mRNA …
H Chen, Z Li, Q Wu, C Yu, JY Yan, Y Bai, S Zhu, M Qian… - Heliyon, 2024 - cell.com
Hyperactivation of ribosome biosynthesis (RiBi) is a hallmark of cancer, and targeting
ribosome biogenesis has emerged as a potential therapeutic strategy. The depletion of …
ribosome biogenesis has emerged as a potential therapeutic strategy. The depletion of …
Human oral mucosa and oral microbiome interactions following supragingival plaque reconstitution in healthy volunteers: a diet-controlled balanced design proof-of …
JLC Mougeot, MF Beckman, DS Morton… - Journal of Oral …, 2023 - Taylor & Francis
Changes in the oral microbiome may contribute to oral pathologies, especially in patients
undergoing cancer therapy. Interactions between oral microbiome and oral mucosa may …
undergoing cancer therapy. Interactions between oral microbiome and oral mucosa may …
Domain definition and preliminary functional exploration of the endonuclease NOBP-1 in Strongyloides stercoralis
H Zhou, W Yuan, W Lei, T Zhou, P Qin, B Zhang… - Parasites & …, 2023 - Springer
Background Ribosome biogenesis is the process of assembling ribosome complexes that
regulate cell proliferation and differentiation with potential regulatory effects on …
regulate cell proliferation and differentiation with potential regulatory effects on …
[HTML][HTML] Identification of Key Genes and Pathways in Duck Fatty Liver Syndrome using Gene Set Enrichment Analysis
X Yang, H Lin, M Wang, X Huang, K Li, W Xia, Y Zhang… - Poultry Science, 2024 - Elsevier
High-laying ducks are often fed high-energy, nutritious feeds to maintain high productivity,
which predisposes them to lipid metabolism disorders and the development of fatty liver …
which predisposes them to lipid metabolism disorders and the development of fatty liver …
Mutations of ribosomal protein genes induce overexpression of catalase in Saccharomyces cerevisiae
CH Hsu, CY Liu, KY Lo - FEMS Yeast Research, 2024 - academic.oup.com
Ribosome assembly defects result in ribosomopathies, primarily caused by inadequate
protein synthesis and induced oxidative stress. This study aimed to investigate the link …
protein synthesis and induced oxidative stress. This study aimed to investigate the link …
Peripheral Blood Gene Expression Profiling Reveals Molecular Pathways Associated with Cervical Artery Dissection
PS Shlapakova, LA Dobrynina… - International Journal of …, 2024 - mdpi.com
Cervical artery dissection (CeAD) is the primary cause of ischemic stroke in young adults.
Monogenic heritable connective tissue diseases account for fewer than 5% of cases of …
Monogenic heritable connective tissue diseases account for fewer than 5% of cases of …
[HTML][HTML] Integrated top-down and bottom-up proteomics mass spectrometry for the characterization of endogenous ribosomal protein heterogeneity
Y Zhang, Q Cai, Y Luo, Y Zhang, H Li - Journal of Pharmaceutical Analysis, 2023 - Elsevier
Ribosomes are abundant, large RNA-protein complexes that are the sites of all protein
synthesis in cells. Defects in ribosomal proteins (RPs), including proteoforms arising from …
synthesis in cells. Defects in ribosomal proteins (RPs), including proteoforms arising from …
[HTML][HTML] Identification of new aptamer BC-3 targeting RPS7 from rapid screening for bladder carcinoma
Y Liu, J Li, H Ou, D Qi, B Hu, Y Xu, J Hu, Y Xiong, L Xia… - Genes & …, 2023 - Elsevier
Aptamers, short single DNA or RNA oligonucleotides, have shown immense application
potential as molecular probes for the early diagnosis and therapy of cancer. However …
potential as molecular probes for the early diagnosis and therapy of cancer. However …