[HTML][HTML] Clinical application of mesenchymal stem cell in regenerative medicine: a narrative review
R Margiana, A Markov, AO Zekiy, MU Hamza… - Stem Cell Research & …, 2022 - Springer
The multipotency property of mesenchymal stem cells (MSCs) has attained worldwide
consideration because of their immense potential for immunomodulation and their …
consideration because of their immense potential for immunomodulation and their …
Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine
Our knowledge of pluripotent stem cell (PSC) biology has advanced to the point where we
now can generate most cells of the human body in the laboratory. PSC-derived …
now can generate most cells of the human body in the laboratory. PSC-derived …
Mechanisms of physiological and pathological cardiac hypertrophy
M Nakamura, J Sadoshima - Nature Reviews Cardiology, 2018 - nature.com
Cardiomyocytes exit the cell cycle and become terminally differentiated soon after birth.
Therefore, in the adult heart, instead of an increase in cardiomyocyte number, individual …
Therefore, in the adult heart, instead of an increase in cardiomyocyte number, individual …
Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential
TG Martin, MA Juarros, LA Leinwand - Nature Reviews Cardiology, 2023 - nature.com
Left ventricular hypertrophy is a leading risk factor for cardiovascular morbidity and mortality.
Although reverse ventricular remodelling was long thought to be irreversible, evidence from …
Although reverse ventricular remodelling was long thought to be irreversible, evidence from …
Identification of long noncoding RNA H19 as a new biomarker and therapeutic target in right ventricular failure in pulmonary arterial hypertension
J Omura, K Habbout, T Shimauchi, WH Wu… - Circulation, 2020 - Am Heart Assoc
Background: Right ventricular (RV) function is the major determinant for both functional
capacity and survival in patients with pulmonary arterial hypertension (PAH). Despite the …
capacity and survival in patients with pulmonary arterial hypertension (PAH). Despite the …
Physiological and pathological cardiac hypertrophy
I Shimizu, T Minamino - Journal of molecular and cellular cardiology, 2016 - Elsevier
The heart must continuously pump blood to supply the body with oxygen and nutrients. To
maintain the high energy consumption required by this role, the heart is equipped with …
maintain the high energy consumption required by this role, the heart is equipped with …
Exosomal circHIPK3 released from hypoxia‐pretreated cardiomyocytes regulates oxidative damage in cardiac microvascular endothelial cells via the miR‐29a/IGF‐1 …
Y Wang, R Zhao, W Liu, Z Wang, J Rong… - Oxidative medicine …, 2019 - Wiley Online Library
Background/Aims. Circular RNAs (circRNAs) are a class of endogenous noncoding RNAs
that regulate gene expression in eukaryotes. Recently, exosomes from cardiomyocytes …
that regulate gene expression in eukaryotes. Recently, exosomes from cardiomyocytes …
[HTML][HTML] Contractile defect caused by mutation in MYBPC3 revealed under conditions optimized for human PSC-cardiomyocyte function
MJ Birket, MC Ribeiro, G Kosmidis, D Ward… - Cell reports, 2015 - cell.com
Maximizing baseline function of human pluripotent stem cell-derived cardiomyocytes (hPSC-
CMs) is essential for their effective application in models of cardiac toxicity and disease …
CMs) is essential for their effective application in models of cardiac toxicity and disease …
Cardioprotection by cardiac progenitor cell-secreted exosomes: role of pregnancy-associated plasma protein-A
Aims Cell therapy trials using cardiac-resident progenitor cells (CPCs) and bone marrow-
derived mesenchymal stem/progenitor cells (BMCs) in patients after myocardial infarction …
derived mesenchymal stem/progenitor cells (BMCs) in patients after myocardial infarction …
Alternative splicing isoforms in health and disease
Alternative splicing (AS) of protein-coding messenger RNAs is an essential regulatory
mechanism in eukaryotic gene expression that controls the proper function of proteins. It is …
mechanism in eukaryotic gene expression that controls the proper function of proteins. It is …