[HTML][HTML] Kirenol: a potential natural lead molecule for a new drug design, development, and therapy for inflammation
Kirenol, a potential natural diterpenoid molecule, is mainly found in Sigesbeckia species.
Kirenol has received a lot of interest in recent years due to its wide range of pharmacological …
Kirenol has received a lot of interest in recent years due to its wide range of pharmacological …
The isolation of water-soluble natural products–challenges, strategies and perspectives
RGS Berlinck, CM Crnkovic, JR Gubiani… - Natural Product …, 2022 - pubs.rsc.org
Covering period: up to 2019 Water-soluble natural products constitute a relevant group of
secondary metabolites notably known for presenting potent biological activities. Examples …
secondary metabolites notably known for presenting potent biological activities. Examples …
Enantioselective Total Synthesis of (+)-KB343
A concise total synthesis of the complex guanidinium toxin KB343 is reported traversing
through an unusual sequence of chemoselective transformations and strategic skeletal …
through an unusual sequence of chemoselective transformations and strategic skeletal …
Stable Isotope-Guided Metabolomics Reveals Polar-Functionalized Fatty-Acylated RiPPs from Streptomyces
Ribosomally synthesized and posttranslationally modified peptides (RiPPs) with polar-
functionalized fatty acyl groups are a rarely found untapped class of natural products …
functionalized fatty acyl groups are a rarely found untapped class of natural products …
Sponges present a core prokaryotic community stable across Tropical Western Atlantic
Sponges are among the earliest lineages of metazoans, with first fossil records dated back
to 890 million years ago. All sponge species present associations with microorganisms to …
to 890 million years ago. All sponge species present associations with microorganisms to …
Atom-economic macrocyclic amphiphile based on guanidinium-functionalized selenacrown ether acting as redox-responsive nanozyme
B Li, Q Xu, X Shen, T Pan, J Shang, Y Ge, Z Qi - Chinese Chemical Letters, 2023 - Elsevier
Control of self-assembly is significant to the preparation of supramolecular materials, but the
control of hydration, responsiveness, dimension, catalysis of macrocyclic amphiphiles in an …
control of hydration, responsiveness, dimension, catalysis of macrocyclic amphiphiles in an …
Discovery, biosynthetic origin, and heterologous production of massinidine, an antiplasmodial alkaloid
BK Lombe, L Winand, J Diettrich, M Tobermann… - Organic …, 2022 - ACS Publications
Bacteria of the genus Massilia represent an underexplored source of bioactive natural
products. Here, we report the discovery of massinidine (1), a guanidine alkaloid with …
products. Here, we report the discovery of massinidine (1), a guanidine alkaloid with …
Structural characterization and immunomodulatory activity of an exopolysaccharide from marine-derived Aspergillus versicolor SCAU141
K Wu, Y Li, Y Lin, B Xu, J Yang, L Mo, R Huang… - International Journal of …, 2023 - Elsevier
Until now, relatively little is known about marine-derived fungal polysaccharides and their
activities. Exopolysaccharide AVP141-A was isolated from the broth of marine-derived …
activities. Exopolysaccharide AVP141-A was isolated from the broth of marine-derived …
Chemical Ecology of the North American Newt Genera Taricha and Notophthalmus
CT Hanifin, Y Kudo, M Yotsu-Yamashita - Progress in the Chemistry of …, 2022 - Springer
Abstract The North American newt genera Taricha and Notophthalmus (order Caudata) are
well known for the combination of potent toxicity, aposematic coloration, and striking defense …
well known for the combination of potent toxicity, aposematic coloration, and striking defense …
Constructing Saturated Guanidinum Heterocycles by Cycloaddition of N-Amidinyliminium Ions with Indoles
TK Allred, MB Shaghafi, PP Chen, Q Tran… - Organic …, 2021 - ACS Publications
We report that structurally complex guanidinium heterocycles can be prepared in one step
by regio-and stereoselective [4+ 2]-cycloadditions of N-amidinyliminium ions with indoles or …
by regio-and stereoselective [4+ 2]-cycloadditions of N-amidinyliminium ions with indoles or …