Depression is widely acknowledged to be a heterogeneous entity, and the need to further
characterize the individual patient who has received this diagnosis in order to personalize …

The issue of the severity of psychiatric disorders has great clinical importance. For example,
severity influences decisions about level of care, and affects decisions to seek government …

Background Evidence-based treatments for adult depression include psychotherapy and
pharmacotherapy, yet little is known about how baseline depression severity moderates …

Introduction: Major depressive disorder (MDD) remains one of the most prevalent mental
health conditions. It is a chronic, relapsing condition and despite multiple treatment options …

Introduction Major depressive disorder (MDD) is a common severe mental disorder,
requiring a tailored and integrated treatment. Several approaches are available including …

Objective Pharmacogenetic studies have identified genetic variants associated with
fluoxetine response in patients with major depression disorder (MDD). The serotonin …

Severity is an important consideration in treatment decision-making for depression. Two
controversies in the treatment of depression are related to the issue of severity. First, are …

Método: Revisión crítica no sistemática de la literatura Resultados: Siguiendo a Horwitz y
Wakefield, planteamos que estas investigaciones presentan problemas metodológicos …

Desvenlafaxine exposure in Korean and US populations was compared using population
pharmacokinetic (PK) analysis. Data from a single‐and multiple‐dose study of …

Depression in the elderly is a significant clinical problem which is likely to endure as an
ongoing issue as the cohort of individuals aged over 65years continues to increase as a …