[HTML][HTML] Red blood cell storage lesion: causes and potential clinical consequences

T Yoshida, M Prudent, A D'Alessandro - Blood Transfusion, 2019 - ncbi.nlm.nih.gov
Red blood cells (RBCs) are a specialised organ that enabled the evolution of multicellular
organisms by supplying a sufficient quantity of oxygen to cells that cannot obtain oxygen …

Real age: red blood cell aging during storage

CG Koch, AI Duncan, P Figueroa, L Dai… - The Annals of thoracic …, 2019 - Elsevier
Background During cold storage, some red blood cell (RBC) units age more rapidly than
others. Yet, the Food and Drug Administration has set a uniform storage limit of 42 days …

Rapid clearance of storage-induced microerythrocytes alters transfusion recovery

C Roussel, A Morel, M Dussiot, M Marin… - Blood, The Journal …, 2021 - ashpublications.org
Permanent availability of red blood cells (RBCs) for transfusion depends on refrigerated
storage, during which morphologically altered RBCs accumulate. Among these, a …

[HTML][HTML] Red blood cells ageing markers: a multi-parametric analysis

M Bardyn, B Rappaz, K Jaferzadeh, D Crettaz… - Blood …, 2017 - ncbi.nlm.nih.gov
Background Red blood cells collected in citrate-phosphate-dextrose can be stored for up to
42 days at 4 C in saline-adenine-glucose-mannitol additive solution. During this controlled …

Donor‐variation effect on red blood cell storage lesion: A close relationship emerges

VL Tzounakas, AG Kriebardis… - PROTEOMICS …, 2016 - Wiley Online Library
Although the molecular pathways leading to the progressive deterioration of stored red
blood cells (RBC storage lesion) and the clinical relevance of storage‐induced changes …

Spherocytic shift of red blood cells during storage provides a quantitative whole cell–based marker of the storage lesion

C Roussel, M Dussiot, M Marin, A Morel… - …, 2017 - Wiley Online Library
BACKGROUND Storage lesion may explain the rapid clearance of up to 25% of transfused
red blood cells (RBCs) in recipients. Several alterations affect stored RBC but a quantitative …

Morphology, membrane nanostructure and stiffness for quality assessment of packed red blood cells

E Kozlova, A Chernysh, V Moroz, V Sergunova… - Scientific reports, 2017 - nature.com
Transfusion of packed red blood cells (PRBC) to patients in critical states is often
accompanied by post-transfusion complications. This may be related with disturbance of …

[HTML][HTML] Duration of red blood cell storage and inflammatory marker generation

C Sut, S Tariket, ML Chou, O Garraud, S Laradi… - Blood …, 2017 - ncbi.nlm.nih.gov
Red blood cell (RBC) transfusion is a life-saving treatment for several pathologies. RBCs for
transfusion are stored refrigerated in a preservative solution, which extends their shelf-life for …

Processing methods and storage duration impact extracellular vesicle counts in red blood cell units

C Gamonet, M Desmarets, G Mourey, S Biichle… - Blood …, 2020 - ashpublications.org
Extracellular vesicles (EVs) are active components of red blood cell (RBC) concentrates and
may be associated with beneficial and adverse effects of transfusion. Elucidating …

Phosphoproteomics and morphology of stored human red blood cells treated by protein tyrosine phosphatases inhibitor

M Bardyn, D Crettaz, B Rappaz, R Hamelin… - Blood …, 2024 - ashpublications.org
The process of protein phosphorylation is involved in numerous cell functions. In particular,
phosphotyrosine (pY) has been reported to play a role in red blood cell (RBC) functions …