[HTML][HTML] A decade of modelling drug release from arterial stents

S McGinty - Mathematical biosciences, 2014 - Elsevier
Drug-eluting stents have revolutionised the treatment of coronary artery disease. These
small medical devices have attracted much interest over the past decade from biologists …

Synthesis of a high characteristics activated carbon from walnut shell for the removal of Cr (VI) and Fe (II) from aqueous solution: single and binary solutes adsorption

M Ghasemi, AA Ghoreyshi, H Younesi… - Iranian Journal of …, 2015 - ijche.com
A high performance activated carbon was synthesized using walnut shell as a solid waste
through a two-step zinc chloride chemical activation-thermal pyrolysis process …

[HTML][HTML] Enhanced drug delivery capabilities from stents coated with absorbable polymer and crystalline drug

WC Carlyle, JB McClain, AR Tzafriri, L Bailey… - Journal of controlled …, 2012 - Elsevier
Current drug eluting stent (DES) technology is not optimized with regard to the
pharmacokinetics of drug delivery. A novel, absorbable-coating sirolimus-eluting stent (AC …

Integrated stent models based on dimension reduction: review and future perspectives

P Zunino, J Tambača, E Cutrì, S Čanić… - Annals of biomedical …, 2016 - Springer
Stent modeling represents a challenging task from both the theoretical and numerical
viewpoints, due to its multi-physics nature and to the complex geometrical configuration of …

Modeling arterial wall drug concentrations following the insertion of a drug-eluting stent

S McGinty, S McKee, RM Wadsworth… - SIAM Journal on Applied …, 2013 - SIAM
A mathematical model of a drug-eluting stent is proposed. The model considers a polymer
region, containing the drug initially, and a porous region, consisting of smooth muscle cells …

Release mechanism and parameter estimation in drug-eluting stent systems: analytical solutions of drug release and tissue transport

S McGinty, S McKee, C McCormick… - … Medicine and Biology …, 2015 - ieeexplore.ieee.org
Drug-eluting stents have significantly improved the treatment of coronary artery disease.
They offer reduced rates of restenosis compared with their bare-metal predecessors and are …

A mass transfer model of temporal drug deposition in artery walls

JP Abraham, JM Gorman, EM Sparrow, JR Stark… - International Journal of …, 2013 - Elsevier
A new mass transfer model has been formulated and implemented for predicting the
penetration of liquid medication into an arterial wall. The model takes separate account of …

A biokinetic model for nickel released from cardiovascular devices

DM Saylor, L Adidharma, JW Fisher… - Regulatory Toxicology and …, 2016 - Elsevier
Many alloys used in cardiovascular device applications contain high levels of nickel, which if
released in sufficient quantities, can lead to adverse health effects. While nickel release from …

[HTML][HTML] Does anisotropy promote spatial uniformity of stent-delivered drug distribution in arterial tissue?

S McGinty, M Wheel, S McKee, C McCormick - International Journal of Heat …, 2015 - Elsevier
In this article we investigate the role of anisotropic diffusion on the resulting arterial wall drug
distribution following stent-based delivery. The arterial wall is known to exhibit anisotropic …

[HTML][HTML] 3D mathematical model for blood flow and non-Fickian mass transport by a coronary drug-eluting stent

E Gudiño, A Sequeira - Applied Mathematical Modelling, 2017 - Elsevier
We propose a fully coupled model for the description of blood flow and mass transport by a
coronary drug-eluting stent. We consider the steady state Navier–Stokes equations to …