Synthesis, antibacterial activities, cytotoxicity, and molecular docking studies of Salicyledene derivatives

Y Belay, A Muller, DT Ndinteh, OA Kolawole… - Journal of Molecular …, 2023 - Elsevier
A series of Schiff bases (1–15) were synthesized by reacting salicylaldehyde with series of
primary amines. Their chemical structures were characterized using 1 H NMR, 13 C {H} …

Therapeutical potential of imines; synthesis, single crystal structure, computational, molecular modeling, and ADMET evaluation

D Tatlidil, MA Raza, N Dege, AA Agar, U Farwa… - ACS …, 2022 - ACS Publications
Imines are multipurpose pharmacophores, simply accessible compounds, and have a broad
range of usage in several areas of chemistry especially in medicine. Two novel compound …

1, 2, 3-triazole and chiral Schiff base hybrids as potential anticancer agents: DFT, molecular docking and ADME studies

Y Belay, A Muller, FS Mokoena, AS Adeyinka… - Scientific Reports, 2024 - nature.com
Abstract A series of novel 1, 2, 3-triazole and chiral Schiff base hybrids 2–6 were
synthesized by Schiff base condensation reaction from pre-prepared parent component of …

Design, synthesis, molecular docking study, and α-glucosidase inhibitory evaluation of novel hydrazide–hydrazone derivatives of 3, 4-dihydroxyphenylacetic acid

H Khan, F Jan, A Shakoor, A Khan, AF AlAsmari… - Scientific Reports, 2024 - nature.com
A series of novel Schiff base derivatives (1–28) of 3, 4-dihydroxyphenylacetic acid were
synthesized in a multi-step reaction. All the synthesized Schiff bases were obtained in high …

Schiff-base ligands containing phenanthroline terminals: synthesis, characterization, biological activities and molecular docking study

G Uluçam, U Bagcı, AŞ Yılmaz, B Yentürk - Spectrochimica Acta Part A …, 2022 - Elsevier
Three new phenanthroline-derived ligands were synthesized by the Schiff base
condensation method. The first ligand was the result of 1, 10-phenanthroline-2 …

Discovery of new Schiff bases of the disalicylic acid scaffold as DNA gyrase and topoisomerase IV inhibitors endowed with antibacterial properties

LH Al-Wahaibi, MA Mahmoud, HA Alzahrani… - Frontiers in …, 2024 - frontiersin.org
DNA gyrase and topoisomerase IV show great potential as targets for antibacterial
medicines. In recent decades, various categories of small molecule inhibitors have been …

Synthesis, structure elucidation, antioxidant properties, and theoretical calculations of new Schiff bases–isatin derivatives

TK Bakır, MS Çavuş, H Muğlu, H Yakan - Research on Chemical …, 2024 - Springer
Isatin-derived Schiff bases are the subject of many studies, finding wide application areas in
polymer technology, pharmaceutical industry, and medicine. In this study, a series of new …

Synthesis, crystal structure, DFT calculations, Hirshfeld surface analysis and molecular docking studies of a new manganese complex

AA Derardja, L Golea, R Benali-Cherif… - Inorganic Chemistry …, 2022 - Elsevier
Mn II-based coordination compound [Mn II (L) 2 (NO 3)(H 2 O) 3] NO 3 (3) has been
synthesized with Shiff's base N 2-benzylidenyl isonicotinic acid hydrazide (2) and (Mn (NO …

[HTML][HTML] Biological Investigation of Nano-Organometallic Agents against Bacteria and Chilo polychrysus

S Patitungkho, K Laead-On, K Patitungkho - Journal of Agricultural …, 2023 - scirp.org
Nanotechnology is the new hope, and is hailed as having the potential to increase the
efficiency of energy consumption, help clean the environment, and solve major health …

Schiff bases complexed with iron and their relation with the life cycle and infection by Schistosoma mansoni

JV da Silva, CC Moreira, EA Montija… - Frontiers in …, 2022 - frontiersin.org
Introduction The trematode Schistosoma mansoni causes schistosomiasis, and this
parasite's life cycle depends on the mollusk Biomphalaria glabrata. The most effective …