Evolutionary dynamics between phages and bacteria as a possible approach for designing effective phage therapies against antibiotic-resistant bacteria
With the increasing global threat of antibiotic resistance, there is an urgent need to develop
new effective therapies to tackle antibiotic-resistant bacterial infections. Bacteriophage …
new effective therapies to tackle antibiotic-resistant bacterial infections. Bacteriophage …
The age of phage: friend or foe in the new dawn of therapeutic and biocontrol applications?
Extended overuse and misuse of antibiotics and other antibacterial agents has resulted in
an antimicrobial resistance crisis. Bacteriophages, viruses that infect bacteria, have …
an antimicrobial resistance crisis. Bacteriophages, viruses that infect bacteria, have …
Bacteriophages of Mycobacterium tuberculosis, their diversity, and potential therapeutic uses: a review
F Zeynali kelishomi, S Khanjani, F Fardsanei… - BMC Infectious …, 2022 - Springer
Tuberculosis (TB) caused by Mycobacterium tuberculosis (M. tuberculosis) is a highly
infectious disease and worldwide health problem. Based on the WHO TB report, 9 million …
infectious disease and worldwide health problem. Based on the WHO TB report, 9 million …
Phage resistance formation and fitness costs of hypervirulent Klebsiella pneumoniae mediated by K2 capsule-specific phage and the corresponding mechanisms
M Tang, Z Huang, X Zhang, J Kong, B Zhou… - Frontiers in …, 2023 - frontiersin.org
Introduction Phage is promising for the treatment of hypervirulent Klebsiella pneumoniae
(hvKP) infections. Although phage resistance seems inevitable, we found that there still was …
(hvKP) infections. Although phage resistance seems inevitable, we found that there still was …
EGFR-targeted photodynamic therapy
L Ulfo, PE Costantini, M Di Giosia, A Danielli… - Pharmaceutics, 2022 - mdpi.com
The epidermal growth factor receptor (EGFR) plays a pivotal role in the proliferation and
metastatization of cancer cells. Aberrancies in the expression and activation of EGFR are …
metastatization of cancer cells. Aberrancies in the expression and activation of EGFR are …
Dendritic systems for bacterial outer membrane disruption as a method of overcoming bacterial multidrug resistance
K Skrzyniarz, D Kuc-Ciepluch, M Lasak… - Biomaterials …, 2023 - pubs.rsc.org
The alarming rise of multi-drug resistant microorganisms has increased the need for new
approaches through the development of innovative agents that are capable of attaching to …
approaches through the development of innovative agents that are capable of attaching to …
Strain-specific predation of Bdellovibrio bacteriovorus on Pseudomonas aeruginosa with a higher range for cystic fibrosis than for bacteremia isolates
C Saralegui, C Herencias, AV Halperin… - Scientific Reports, 2022 - nature.com
This work aimed to evaluate the predatory activity of Bdellovibrio bacteriovorus 109J on
clinical isolates of Pseudomonas aeruginosa selected from well-characterized collections of …
clinical isolates of Pseudomonas aeruginosa selected from well-characterized collections of …
The mutation in wbaP cps gene cluster selected by phage-borne depolymerase abolishes capsule production and diminishes the virulence of Klebsiella pneumoniae
M Kaszowska, G Majkowska-Skrobek… - International journal of …, 2021 - mdpi.com
Klebsiella pneumoniae is considered one of the most critical multidrug-resistant pathogens
and urgently requires new therapeutic strategies. Capsular polysaccharides (CPS) …
and urgently requires new therapeutic strategies. Capsular polysaccharides (CPS) …
Bacteriophages: a potential game changer in food processing industry
V Chaudhary, P Kajla, D Lather… - Critical Reviews in …, 2024 - Taylor & Francis
In the food industry, despite the widespread use of interventions such as preservatives and
thermal and non-thermal processing technologies to improve food safety, incidences of …
thermal and non-thermal processing technologies to improve food safety, incidences of …
Bacteriophage steering of Burkholderia cenocepacia toward reduced virulence and increased antibiotic sensitivity
MK Ruest, BSI Supina, JJ Dennis - Journal of Bacteriology, 2023 - Am Soc Microbiol
Bacteria frequently encounter selection pressure from both antibiotics and lytic phages, but
little is known about the interactions between antibiotics and phages. This study provides …
little is known about the interactions between antibiotics and phages. This study provides …