Evolutionary dynamics between phages and bacteria as a possible approach for designing effective phage therapies against antibiotic-resistant bacteria

M Hasan, J Ahn - Antibiotics, 2022 - mdpi.com
With the increasing global threat of antibiotic resistance, there is an urgent need to develop
new effective therapies to tackle antibiotic-resistant bacterial infections. Bacteriophage …

The age of phage: friend or foe in the new dawn of therapeutic and biocontrol applications?

AY Hassan, JT Lin, N Ricker, H Anany - Pharmaceuticals, 2021 - mdpi.com
Extended overuse and misuse of antibiotics and other antibacterial agents has resulted in
an antimicrobial resistance crisis. Bacteriophages, viruses that infect bacteria, have …

Bacteriophages of Mycobacterium tuberculosis, their diversity, and potential therapeutic uses: a review

F Zeynali kelishomi, S Khanjani, F Fardsanei… - BMC Infectious …, 2022 - Springer
Tuberculosis (TB) caused by Mycobacterium tuberculosis (M. tuberculosis) is a highly
infectious disease and worldwide health problem. Based on the WHO TB report, 9 million …

Phage resistance formation and fitness costs of hypervirulent Klebsiella pneumoniae mediated by K2 capsule-specific phage and the corresponding mechanisms

M Tang, Z Huang, X Zhang, J Kong, B Zhou… - Frontiers in …, 2023 - frontiersin.org
Introduction Phage is promising for the treatment of hypervirulent Klebsiella pneumoniae
(hvKP) infections. Although phage resistance seems inevitable, we found that there still was …

EGFR-targeted photodynamic therapy

L Ulfo, PE Costantini, M Di Giosia, A Danielli… - Pharmaceutics, 2022 - mdpi.com
The epidermal growth factor receptor (EGFR) plays a pivotal role in the proliferation and
metastatization of cancer cells. Aberrancies in the expression and activation of EGFR are …

Dendritic systems for bacterial outer membrane disruption as a method of overcoming bacterial multidrug resistance

K Skrzyniarz, D Kuc-Ciepluch, M Lasak… - Biomaterials …, 2023 - pubs.rsc.org
The alarming rise of multi-drug resistant microorganisms has increased the need for new
approaches through the development of innovative agents that are capable of attaching to …

Strain-specific predation of Bdellovibrio bacteriovorus on Pseudomonas aeruginosa with a higher range for cystic fibrosis than for bacteremia isolates

C Saralegui, C Herencias, AV Halperin… - Scientific Reports, 2022 - nature.com
This work aimed to evaluate the predatory activity of Bdellovibrio bacteriovorus 109J on
clinical isolates of Pseudomonas aeruginosa selected from well-characterized collections of …

The mutation in wbaP cps gene cluster selected by phage-borne depolymerase abolishes capsule production and diminishes the virulence of Klebsiella pneumoniae

M Kaszowska, G Majkowska-Skrobek… - International journal of …, 2021 - mdpi.com
Klebsiella pneumoniae is considered one of the most critical multidrug-resistant pathogens
and urgently requires new therapeutic strategies. Capsular polysaccharides (CPS) …

Bacteriophages: a potential game changer in food processing industry

V Chaudhary, P Kajla, D Lather… - Critical Reviews in …, 2024 - Taylor & Francis
In the food industry, despite the widespread use of interventions such as preservatives and
thermal and non-thermal processing technologies to improve food safety, incidences of …

Bacteriophage steering of Burkholderia cenocepacia toward reduced virulence and increased antibiotic sensitivity

MK Ruest, BSI Supina, JJ Dennis - Journal of Bacteriology, 2023 - Am Soc Microbiol
Bacteria frequently encounter selection pressure from both antibiotics and lytic phages, but
little is known about the interactions between antibiotics and phages. This study provides …