Sigma-1 receptor agonists are reported to augment and antagonists block the rewarding
effects of drugs of abuse. However, their effect on reinstatement of ethanol-induced …

Major Depressive Disorder (MDD) is a common mental illness that causes significant
disability and declining quality of life. An overlap of multiple factors can be involved in the …

Chronic stress leads to hypofunction of the medial prefrontal cortex (mPFC), mechanisms of
which remain to be determined. Enhanced activation of GABAergic of parvalbumin (PV) …

Anxiety disorder is one of the most prevalent psychiatric disorders. The high prevalence of
comorbid gastrointestinal disorders and anxiety, as well as various limitations in current …

Objectives: The purpose of this study was to examine the antidepressant and anxiolytic
effects of the hydroalcoholic extract of Adiantum capillus-veneris (rich in flavonoids with …

The leaves of Scurrula parasitica were effectively extracted by means of cold extraction
method. Fractionation and purification of the n-hexane, ethyl acetate, and methanol crude …

The aim of our study was to determine the role of corticotropin-releasing factor (CRF), the
urocortins (Ucn1, Ucn2 and Ucn3) and their receptors (CRF 1 and CRF 2) in the sociability …

Context: Neuropsychiatric disorders, like anxiety and depression, are global problems for
clinical researchers in neurology. Recently, some authors have shown neuroprotective and …

We investigated effects of the hydroalcoholic extract of Rosa сanina (dog rose) petals on
behavior of rats in the elevated plus-maze (EPM) test; adult male Wistar rats weighing 200 …

Shahar S, Aziz AF, Ismail SNA, et al. The effect of Polygonum minus extract on cognitive and
psychosocial parameters according to mood status among middle-aged women: a …