Maternal–fetal nutrient transport in pregnancy pathologies: the role of the placenta

KE Brett, ZM Ferraro, J Yockell-Lelievre… - International journal of …, 2014 - mdpi.com
Appropriate in utero growth is essential for offspring development and is a critical contributor
to long-term health. Fetal growth is largely dictated by the availability of nutrients in maternal …

The risk of maternal obesity to the long‐term health of the offspring

JR O'Reilly, RM Reynolds - Clinical endocrinology, 2013 - Wiley Online Library
The prevalence of maternal obesity has risen dramatically in recent years, with
approximately one in five pregnant women in the UK now classed as obese (body mass …

Position of the academy of nutrition and dietetics: obesity, reproduction, and pregnancy outcomes

J Stang, LG Huffman - Journal of the Academy of Nutrition and Dietetics, 2016 - Elsevier
It is the position of the Academy of Nutrition and Dietetics that all women of reproductive age
receive education about maternal and fetal risks associated with prepregnancy obesity …

Optimising sample collection for placental research

GJ Burton, NJ Sebire, L Myatt, D Tannetta, YL Wang… - Placenta, 2014 - Elsevier
Biobanks provide an important repository of samples for research purposes. However, for
those samples to reflect the in vivo state, and for experimental reliability and reproducibility …

Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies

N Jansson, FJ Rosario, F Gaccioli… - The Journal of …, 2013 - academic.oup.com
Context: Babies of obese women are often large at birth, which is associated with perinatal
complications and metabolic syndrome later in life. The mechanisms linking maternal …

Intrahepatic fat is increased in the neonatal offspring of obese women with gestational diabetes

DE Brumbaugh, P Tearse, M Cree-Green… - The Journal of …, 2013 - Elsevier
OBJECTIVES: To assess precision magnetic resonance imaging in the neonate and
determine whether there is an early maternal influence on the pattern of neonatal fat …

Hypoxia: from placental development to fetal programming

L Fajersztajn, MM Veras - Birth defects research, 2017 - Wiley Online Library
Hypoxia may influence normal and different pathological processes. Low oxygenation
activates a variety of responses, many of them regulated by hypoxia‐inducible factor 1 …

Developmental programming of obesity and diabetes in mouse, monkey, and man in 2018: where are we headed?

JE Friedman - Diabetes, 2018 - Am Diabetes Assoc
Childhood obesity and its comorbidities continue to accelerate across the globe. Two-thirds
of pregnant women are obese/overweight, as are 20% of preschoolers. Gestational diabetes …

Placental weight and efficiency in relation to maternal body mass index and the risk of pregnancy complications in women delivering singleton babies

JM Wallace, GW Horgan, S Bhattacharya - Placenta, 2012 - Elsevier
Herein we report placental weight and efficiency in relation to maternal BMI and the risk of
pregnancy complications in 55,105 pregnancies. Adjusted placental weight increased with …

In Utero Exposures, Infant Growth, and DNA Methylation of Repetitive Elements and Developmentally Related Genes in Human Placenta

CS Wilhelm-Benartzi, EA Houseman… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: Fetal programming describes the theory linking environmental conditions
during embryonic and fetal development with risk of diseases later in life. Environmental …