Recent advances on emerging nanomaterials for diagnosis and treatment of inflammatory bowel disease

W Fu, L Xu, Z Chen, L Kan, Y Ma, H Qian… - Journal of Controlled …, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a chronic idiopathic inflammatory disorder that affects
the entire gastrointestinal tract and is associated with an increased risk of colorectal cancer …

Innovative technologies on the fabrication of 3D/4D smart hydrogels and its biomedical applications-A compendious review

U Shashikumar, A Sarawat, K Deshmukh… - Advances in Colloid and …, 2024 - Elsevier
Repairing and regenerating damaged tissues or organs and restoring their functioning has
been the ultimate aim of medical innovations. Reviving healthcare blends tissue …

Nanotechnology-enabled M2 macrophage polarization and ferroptosis inhibition for targeted inflammatory bowel disease treatment

Y Zhao, W Yin, Z Yang, J Sun, J Chang, L Huang… - Journal of Controlled …, 2024 - Elsevier
Transforming macrophages into the anti-inflammatory M2 phenotype could markedly
strengthen inflammatory bowel disease (IBD) treatment, which is considered as a promising …

Oral alginate microspheres for the efficient site-specific delivery of epidermal growth factor attenuated murine ulcerative colitis via repairing the mucosal barrier

B Chen, D Li, B Tong, L Wang, H Lin, H Xu… - International Journal of …, 2024 - Elsevier
Ulcerative colitis (UC) is a chronic bowel inflammatory disease affecting the colorectum.
Epidermal growth factor (EGF) has been demonstrated to be effective to counteract UC …

Polyphenolic Nanoparticle-Modified Probiotics for Microenvironment Remodeling and Targeted Therapy of Inflammatory Bowel Disease

Q Hu, J Li, T Wang, X Xu, Y Duan, Y Jin - ACS nano, 2024 - ACS Publications
Inflammatory bowel diseases (IBDs) refer to multifaceted disorders in the intestinal
microenvironment and microbiota homeostasis. In view of the broad bioactivity and high …

Colon‐Targeted Oral Delivery of Hydroxyethyl Starch–Curcumin Microcapsules Loaded with Multiple Drugs Alleviates DSS‐Induced Ulcerative Colitis in Mice

D Huang, M Zou, C Xu, Y Wang, Z Xu… - Macromolecular …, 2024 - Wiley Online Library
Combination therapy through colon‐targeted oral delivery of multiple drugs presents a
promising approach for effectively treating ulcerative colitis (UC). However, the codelivery of …

DNA Nanostructures Treat Inflammatory Bowel Disease through ROS Scavenging and Gut Microbiota Modulation

J Ge, B Jia, Y Wang, Y Ma, X Sun… - Advanced Functional …, 2024 - Wiley Online Library
Inflammatory bowel disease (IBD) encompasses a collection of chronic inflammatory
conditions impacting the gastrointestinal tract, with a discernible global rise in prevalence …

Hydrogel Derived from Decellularized Porcine Small Intestinal Submucosa as a Physical Shielding Repaired the Gut Epithelial Barrier of Murine Ulcerative Colitis

H Pan, B Ding, Z Jiang, J Wang, D Li… - Advanced Functional …, 2024 - Wiley Online Library
Ulcerative colitis (UC) is associated with the shedding of the gut mucus. Decellularized
porcine small intestinal submucosa (SIS‐ECM) contains numerous active forms of …

Growth Factors-Loaded Temperature-Sensitive Hydrogel as Biomimetic Mucus Attenuated Murine Ulcerative Colitis via Repairing the Mucosal Barriers

D Li, J Shangguan, F Yu, G Lin, H Pan… - … Applied Materials & …, 2024 - ACS Publications
The pathogenesis of ulcerative colitis (UC) is associated with the shedding of the gut mucus.
Herein, inspired by the biological functions of mucus, growth factors-loaded in situ hydrogel …

Étude de la reconnaissance des Escherichia coli adhérents et invasifs (AIEC) associés à la maladie de Crohn par l'autophagie: identification des récepteurs …

A da Silva - 2023 - theses.hal.science
La maladie de Crohn (MC) est une maladie inflammatoire chronique de l'intestin, dont
l'étiologie est multifactorielle. Elle résulte de l'interaction complexe entre des prédispositions …