The vortex—an early predictor of cardiovascular outcome?

G Pedrizzetti, G La Canna, O Alfieri… - Nature Reviews Cardiology, 2014 - nature.com
Blood motion in the heart features vortices that accompany the redirection of jet flows
towards the outlet tracks. Vortices have a crucial role in fluid dynamics. The stability of …

Left ventricular structure and function: basic science for cardiac imaging

PP Sengupta, J Korinek, M Belohlavek, J Narula… - Journal of the American …, 2006 - jacc.org
The myofiber geometry of the left ventricle (LV) changes gradually from a right-handed helix
in the subendocardium to a left-handed helix in the subepicardium. In this review, we …

[HTML][HTML] Electro-mechanical whole-heart digital twins: a fully coupled multi-physics approach

T Gerach, S Schuler, J Fröhlich, L Lindner… - Mathematics, 2021 - mdpi.com
Mathematical models of the human heart are evolving to become a cornerstone of precision
medicine and support clinical decision making by providing a powerful tool to understand …

A comparison of monodomain and bidomain reaction-diffusion models for action potential propagation in the human heart

M Potse, B Dubé, J Richer, A Vinet… - IEEE Transactions on …, 2006 - ieeexplore.ieee.org
A bidomain reaction-diffusion model of the human heart was developed, and potentials
resulting from normal depolarization and repolarization were compared with results from a …

Cardiac mechanics revisited: the relationship of cardiac architecture to ventricular function

G Buckberg, JIE Hoffman, A Mahajan, S Saleh… - Circulation, 2008 - Am Heart Assoc
The keynote to understanding cardiac function is recognizing the underlying architecture
responsible for the contractile mechanisms that produce the narrowing, shortening …

Second‐order motion‐compensated spin echo diffusion tensor imaging of the human heart

CT Stoeck, C von Deuster, M Genet… - Magnetic resonance …, 2016 - Wiley Online Library
Purpose Myocardial microstructure has been challenging to probe in vivo. Spin echo–based
diffusion‐weighted sequences allow for single‐shot acquisitions but are highly sensitive to …

Fully coupled fluid‐electro‐mechanical model of the human heart for supercomputers

A Santiago, J Aguado‐Sierra… - … journal for numerical …, 2018 - Wiley Online Library
In this work, we present a fully coupled fluid‐electro‐mechanical model of a 50th percentile
human heart. The model is implemented on Alya, the BSC multi‐physics parallel code …

Diffusion tensor magnetic resonance imaging mapping the fiber architecture remodeling in human myocardium after infarction: correlation with viability and wall …

MT Wu, WYI Tseng, MYM Su, CP Liu, KR Chiou… - Circulation, 2006 - Am Heart Assoc
Background—Diffusion tensor magnetic resonance imaging (DT-MRI) provides a means for
nondestructive characterization of myocardial architecture. We used DT-MRI to investigate …

In vivo diffusion tensor MRI of the human heart: reproducibility of breath‐hold and navigator‐based approaches

S Nielles‐Vallespin, C Mekkaoui… - Magnetic resonance …, 2013 - Wiley Online Library
The aim of this study was to implement a quantitative in vivo cardiac diffusion tensor imaging
(DTI) technique that was robust, reproducible, and feasible to perform in patients with …

What is the heart? Anatomy, function, pathophysiology, and misconceptions

GD Buckberg, NC Nanda, C Nguyen… - Journal of cardiovascular …, 2018 - mdpi.com
Cardiac dynamics are traditionally linked to a left ventricle, right ventricle, and septum
morphology, a topography that differs from the heart's five-century-old anatomic description …