Origin and consequences of necroinflammation

M Sarhan, WG Land, W Tonnus… - Physiological …, 2018 - journals.physiology.org
When cells undergo necrotic cell death in either physiological or pathophysiological settings
in vivo, they release highly immunogenic intracellular molecules and organelles into the …

[HTML][HTML] Transplantation and damage-associated molecular patterns (DAMPs)

WG Land, P Agostinis, S Gasser, AD Garg… - American Journal of …, 2016 - Elsevier
Upon solid organ transplantation and during cancer immunotherapy, cellular stress
responses result in the release of damage-associated molecular patterns (DAMPs). The …

Heme Oxygenase-1 in liver transplant ischemia-reperfusion injury: From bench-to-bedside

H Hirao, KJ Dery, S Kageyama, K Nakamura… - Free Radical Biology …, 2020 - Elsevier
Hepatic ischemia-reperfusion injury (IRI), a major risk factor for early allograft dysfunction
(EAD) and acute or chronic graft rejection, contributes to donor organ shortage for life-saving …

Micro‐vesicles derived from human Wharton's Jelly mesenchymal stromal cells mitigate renal ischemia‐reperfusion injury in rats after cardiac death renal …

X Wu, T Yan, Z Wang, X Wu, G Cao… - Journal of Cellular …, 2018 - Wiley Online Library
The purpose of the present study was to investigate the possible therapeutic effects of the
human Wharton‐Jelly mesenchymal stromal cells derived micro‐vesicles (hWJMSCs‐MVs) …

The human immune response to cadaveric and living donor liver allografts

A Hann, DC Osei-Bordom, DAH Neil, V Ronca… - Frontiers in …, 2020 - frontiersin.org
The liver is an important contributor to the human immune system and it plays a pivotal role
in the creation of both immunoreactive and tolerogenic conditions. Liver transplantation …

The distinct innate immune response of warm ischemic injured livers during continuous normothermic machine perfusion

J Blondeel, N Gilbo, V Heedfeld, T Wylin… - International Journal of …, 2023 - mdpi.com
Although normothermic machine perfusion (NMP) provides superior preservation of liver
grafts compared to static cold storage and allows for viability testing of high-risk grafts, its …

Limb remote ischemic conditioning of the recipient protects the liver in a rat model of arterialized orthotopic liver transplantation

Z Czigany, C Bleilevens, C Beckers, C Stoppe… - PloS one, 2018 - journals.plos.org
Background Ischemic-reperfusion (IR) injury still represents a major concern in clinical
transplantation, especially in the era of extreme organ shortage and extended criteria donor …

A new organ preservation solution for static cold storage of the liver. Amniotic fluid

B Büyük, T Demirci, Y Adalı, HA Eroğlu - Acta Cirurgica Brasileira, 2019 - SciELO Brasil
Purpose: To evaluate the effect of amniotic fluid in liver preservation in organ
transplantation, and compare it with standard preservation solutions. Methods: The groups …

实时超声弹性成像技术对原位肝移植患者术后缺血型胆道病变临床评估价值分析

丁蕾, 张振, 刘福全 - 实用肝脏病杂志, 2018 - manu43.magtech.com.cn
目的探讨应用实时超声弹性成像技术对原位肝移植术后缺血型胆道病变的临床评估价值.
方法2013 年1 月~ 2017 年1 月在我院接受肝移植患者52 例, 使用彩色多普勒超声和实时超声 …

Hepatocellular uptake of cyclodextrin‐complexed curcumin during liver preservation: A feasibility study

SA Saidi, N Meurisse, I Jochmans… - … & Drug Disposition, 2018 - Wiley Online Library
The increasing demand for donor organs and the decreasing organ quality is prompting
research toward new methods to reduce ischemia reperfusion injury (IRI). Several strategies …