Polymeric materials have been applied in therapeutic applications, such as drug delivery
and tissue regeneration, for decades owing to their biocompatibility and suitable mechanical …

A major goal of cancer nanotherapy is to use nanoparticles as carriers for targeted delivery
of anti-tumour agents. The drug–carrier association after intravenous administration is …

Although several anticancer drugs have been introduced as chemotherapeutic agents, the
effective treatment of cancer remains a challenge. Major limitations in the application of …

Musculoskeletal diseases such as osteoporosis are recognized as major public health
problems worldwide. Many novel therapeutic agents have been identified for the treatment …

Many drug molecules that are currently in the market suffer from short half-life, poor
absorption, low specificity, rapid degradation, and resistance development. The design and …

Activated signaling cascades in the proximal tubular cells of the kidneys play a crucial role in
the development of tubulointerstitial fibrosis. Inhibition of these signaling cascades with …

To obtain a pH-sensitive multifunctional polyurethane micelle drug carrier, a novel pH-
sensitive macrodiol containing acid-cleavable hydrazone linkers, poly (ε-caprolactone) …

Although folate exhibits many advantages over other targeting ligands, it has one major
defect: poor water solubility. Once it was conjugated to hydrophilic drug carrier such as N-(2 …

N-Acetyl-l-cysteine (NAC) is an antioxidant and anti-inflammatory agent with significant
potential in clinical applications including stroke and neuroinflammation. The drug shows …

The synthesis of a variety of core functionalized PEGylated polyester dendrimers and their in
vitro and in vivo properties are described in this report. These water-soluble dendrimers …