For the past three decades, pharmaceutical research has been mainly converging to novel
carrier systems and nanoparticulate colloidal technologies for drug delivery, such as …

We synthesized N-(2-hydroxypropyl) methacrylamide polymer conjugated with zinc
protoporphyrin (HPMA-ZnPP) and evaluated its application for tumor detection by imaging …

Various conjugates of anticancer drug doxorubicin (DOX) covalently attached via
hydrolytically degradable hydrazone bond to water-soluble N-(2-hydroxypropyl) …

Polymer nanomedicines are very attractive to improve the delivery of chemotherapeutics.
Polymer conjugates and other polymer‐based nanocarriers allow to increase plasma half …

Synthetic polymers are of increasing interest as therapeutic agents owing to their enhanced
pharmacokinetic profiles relative to small molecule drugs. Multifunctional polymers are now …

The preparation of core-shell polymeric nanoparticles simultaneously loaded with docetaxel
(DTXL) and doxorubicin (DOX) is reported herein. The self-assembly of the aliphatic …

Purpose In this study, pH-sensitive poly (2-ethyl-2-oxazoline)-poly (lactic acid)-poly (β-amino
ester)(PEOz-PLA-PBAE) triblock copolymers were synthesized and were conjugated with an …

Antimicrobial peptides (AMPs) are a promising class of antimicrobial agents that have been
garnering increasing attention as resistance renders many conventional antibiotics …

Highlights•HPMA (N-2-hydroxypropylmethacrylamide) is an emerging polymeric alternative
for drug delivery applications.•HPMA can be potentially conjugated to develop copolymers …

In this study, three PEGylated doxorubicin (DOX) prodrugs with acid-labile acetal and
carbamate linkages have been prepared via the combination of Cu (I)-catalyzed Huisgen 1 …