The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the
current COVID-19 pandemic. An unbalanced immune response, characterized by a weak …

RNA-binding proteins (RBPs) are typically thought of as proteins that bind RNA through one
or multiple globular RNA-binding domains (RBDs) and change the fate or function of the …

Abstract Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory
Syndrome (MERS) are the most severe coronavirus (CoV)-associated diseases in humans …

Cells respond to viral infections through sensors that detect non-self-molecules, and through
effectors, which can have direct antiviral activities or adapt cell physiology to limit viral …

The proper processing, export, localization, translation, and degradation of mRNAs are
necessary for regulation of gene expression. These processes are controlled by mRNA …

In the past century, few areas of biology advanced as much as our understanding of the
pathways of intermediary metabolism. Initially considered unimportant in terms of gene …

Protein kinase RNA-activated (PKR) induces immune response by sensing viral double-
stranded RNAs (dsRNAs). However, growing evidence suggests that PKR can also be …

Mitochondria participate in a wide range of cellular processes. One essential function of
mitochondria is to be a platform for antiviral signaling proteins during the innate immune …

Viruses are obligate intracellular parasites; they heavily depend on the host cell machinery
to effectively replicate and produce new progeny virus particles. Following viral infection …

Although chemotherapy can stimulate antitumor immunity by inducing interferon (IFN)
response, the functional role of tumor-associated macrophages in this scenario remains …