Background: Sepsis is a life-threatening condition responsible for up to 20% of all global
deaths. Kidneys are among the most common organs implicated, yet the pathogenesis of …

Extracorporeal membrane oxygenation (ECMO) is a modified cardiopulmonary bypass
(CPB) circuit capable of providing prolonged cardiorespiratory support. Recent …

Abnormal changes of the microvasculature are reported to be key evidence of the
development of several critical diseases, including cancer, progressive kidney disease, and …

Novel therapeutic interventions are required to prevent or treat AKI. To expedite progress in
this regard, a consensus conference held by the Acute Dialysis Quality Initiative was …

METHODS: We included 87 patients with cirrhosis and 27 healthy controls in this
prospective cohort study. The population comprised patients with compensated cirrhosis (n …

Introduction The pathophysiology of acute kidney injury (AKI) in sepsis is ill defined. We
investigated parameters associated with low glomerular filtration, and their predictive value …

Established as a method to study anatomic changes, such as renal tumors or atherosclerotic
vascular disease, magnetic resonance imaging (MRI) to interrogate renal function has only …

Sepsis‐induced acute kidney injury (SI‐AKI) is common and associated with high mortality.
Survivors are at increased risk of chronic kidney disease. The precise mechanism …

Acute kidney injury (AKI) is a risk factor for the development of chronic kidney disease
(CKD). One mechanism for this phenomenon is renal microvascular rarefaction and …

Sepsis-associated acute kidney injury (s-AKI) has a staggering impact in patients and lacks
any treatment. Incomplete understanding of the pathogenesis of s-AKI is a major barrier to …