[HTML][HTML] CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis

H Zhang, Z Deng, Y Wang, X Zheng, L Zhou, S Yan… - Iscience, 2023 - cell.com
Septic acute kidney injury (S-AKI), the most common type of acute kidney injury (AKI), is
intimately related to pyroptosis and oxidative stress in its pathogenesis. Carboxy-terminus of …

Renal tubular cell mitochondrial dysfunction occurs despite preserved renal oxygen delivery in experimental septic acute kidney injury

N Arulkumaran, S Pollen, E Greco… - Critical care …, 2018 - journals.lww.com
Objective: To explain the paradigm of significant renal functional impairment despite
preserved hemodynamics and histology in sepsis-induced acute kidney injury. Design …

Septic acute kidney injury patients in emergency department: The risk factors and its correlation to serum lactate

YC Hsu, CW Hsu - The American journal of emergency medicine, 2019 - Elsevier
Background Acute kidney injury (AKI) is a common complication in septic patients, imposing
a heavy burden of illness in terms of morbidity and mortality. Serum lactate is a widely used …

Renal MRI: from nephron to NMR signal

O Bane, E Seeliger, E Cox, J Stabinska… - Journal of Magnetic …, 2023 - Wiley Online Library
Renal diseases pose a significant socio‐economic burden on healthcare systems. The
development of better diagnostics and prognostics is well‐recognized as a key strategy to …

Renal oxygenation and hemodynamics in kidney injury

A Bullen, ZZ Liu, M Hepokoski, Y Li, P Singh - Nephron, 2017 - karger.com
Acute kidney injury (AKI) continues to be a major therapeutic challenge. Despite significant
advances made in cellular and molecular pathophysiology of AKI, major gaps in knowledge …

Imaging-based deep learning in kidney diseases: recent progress and future prospects

M Zhang, Z Ye, E Yuan, X Lv, Y Zhang, Y Tan, C Xia… - Insights into …, 2024 - Springer
Kidney diseases result from various causes, which can generally be divided into neoplastic
and non-neoplastic diseases. Deep learning based on medical imaging is an established …

New imaging techniques in AKI

NM Selby, J Duranteau - Current opinion in critical care, 2020 - journals.lww.com
CEUS and multiparametric renal MRI are promising imaging techniques but more evidence
is needed to show how they can first be more widely used in a research setting to test key …

Maresin conjugates in tissue regeneration-1 suppresses ferroptosis in septic acute kidney injury

J Xiao, Q Yang, Y Zhang, H Xu, Y Ye, L Li, Y Yang… - Cell & Bioscience, 2021 - Springer
Background Ferroptosis is unique among different types of regulated cell death and closely
related to organ injury. Whether ferroptosis occurs in sepsis-associated acute kidney injury …

New insights in acute kidney failure in the critically ill

Z Ricci, C Ronco - Swiss medical weekly, 2012 - smw.ch
The term acute kidney injury (AKI) has been recently coined by a large panel of international
experts in place of the former expression “acute renal failure”. This change has been …

Endothelial glycocalyx—the battleground for complications of sepsis and kidney injury

JW Song, J Zullo, M Lipphardt… - Nephrology Dialysis …, 2018 - academic.oup.com
After briefly discussing endothelial glycocalyx and its role in vascular physiology and renal
disease, this overview focuses on its degradation very early in the course of microbial …