The importance of personalized blood pressure management is well recognized. Because
renal pressure–flow relationships may vary among patients, understanding how renal …

Background Changes in renal perfusion may play a pathophysiological role in hypertension
and kidney disease, however to date, no method for renal blood flow (RBF) determination in …

This article is one of ten reviews selected from the Annual Update in Intensive Care and
Emergency Medicine 2013 and co-published as a series in Critical Care. Other articles in …

Objectives The aim of this study was to describe the population pharmacokinetics of
vancomycin during prolonged intermittent renal replacement therapy (PIRRT) in critically ill …

This article reviews the application of contrast-enhanced ultrasound (CEUS) in gauging
renal microvascular perfusion in diverse renal diseases. The unique nature of the contrast …

Rational drug use in special populations is a clinical problem that doctors and pharma-cists
must consider seriously. Neonates are the most physiologically immature and vulnerable to …

Characterizing structural and tissue abnormalities of the kidney is fundamental to
understanding kidney disease. Functional multi‐parametric renal magnetic resonance …

Clinical Background: Clinical infections and its most severe forms sepsis and septic shock
are commonly associated with changes in kidney function. This acute kidney injury (AKI) is …

Acute kidney injury (AKI) affects approximately 40% of critically ill patients [1] using the latest
clinical Kidney Diseases: Improving Global Outcomes (KDIGO) criteria based on both serum …

Background Both sepsis and AKI are diseases of major concern in intensive care unit (ICU).
This study aimed to evaluate the excess mortality attributable to sepsis for acute kidney …