Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Advances of medical nanorobots for future cancer treatments

X Kong, P Gao, J Wang, Y Fang, KC Hwang - Journal of Hematology & …, 2023 - Springer
Early detection and diagnosis of many cancers is very challenging. Late stage detection of a
cancer always leads to high mortality rates. It is imperative to develop novel and more …

[HTML][HTML] Current approaches of nanomedicines in the market and various stage of clinical translation

X Shan, X Gong, J Li, J Wen, Y Li, Z Zhang - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Compared with traditional drug therapy, nanomedicines exhibit intriguing biological features
to increase therapeutic efficiency, reduce toxicity and achieve targeting delivery. This review …

Strategies to manipulate the performance of aptamers in SELEX, post-SELEX and microenvironment

S Qi, N Duan, IM Khan, X Dong, Y Zhang, S Wu… - Biotechnology …, 2022 - Elsevier
Aptamers are short single-stranded DNA or RNA oligonucleotides isolated from randomized
libraries, presenting high affinity and specificity toward targets with similar to antibodies …

Tunable metal–organic frameworks assist in catalyzing DNAzymes with amplification platforms for biomedical applications

X Zhu, J Xu, G Ling, P Zhang - Chemical Society Reviews, 2023 - pubs.rsc.org
Various binding modes of tunable metal organic frameworks (MOFs) and functional
DNAzymes (Dzs) synergistically catalyze the emergence of abundant functional …

Intelligent Micro‐/Nanorobots for Cancer Theragnostic

J Wang, Y Dong, P Ma, Y Wang, F Zhang… - Advanced …, 2022 - Wiley Online Library
Cancer is one of the most intractable diseases owing to its high mortality rate and lack of
effective diagnostic and treatment tools. Advancements in micro‐/nanorobot (MNR)‐assisted …

An intelligent nanomachine guided by DNAzyme logic system for precise chemodynamic therapy

Z Wang, J Yang, G Qin, C Zhao… - Angewandte Chemie …, 2022 - Wiley Online Library
The intelligent nanomachine usually has a control center to carry out self‐regulation.
Unfortunately, most of the nanomaterials for chemodynamic therapy (CDT) do not have such …

DNA Origami: From Molecular Folding Art to Drug Delivery Technology

Q Jiang, Y Shang, Y Xie, B Ding - Advanced Materials, 2024 - Wiley Online Library
DNA molecules that store genetic information in living creatures can be repurposed as
building blocks to construct artificial architectures, ranging from the nanoscale to the …

DNA logic circuits for cancer theranostics

J Chen, S Fu, C Zhang, H Liu, X Su - Small, 2022 - Wiley Online Library
Cancer diagnosis and therapeutics (theranostics) based on the tumor microenvironment
(TME) and biomarkers has been an emerging approach for precision medicine. DNA …

Dynamic reconfigurable DNA nanostructures, networks and materials

J Wang, Z Li, I Willner - Angewandte Chemie, 2023 - Wiley Online Library
DNA nanotechnology relies on the structural and functional information encoded in nucleic
acids. Specifically, the sequence‐guided reconfiguration of nucleic acids by auxiliary …