[HTML][HTML] Microbial extracellular vesicles contribute to antimicrobial resistance

B Jiang, Y Lai, W Xiao, T Zhong, F Liu, J Gong… - Plos …, 2024 - journals.plos.org
With the escalating global antimicrobial resistance crisis, there is an urgent need for
innovative strategies against drug-resistant microbes. Accumulating evidence indicates …

Beyond resistance: antifungal heteroresistance and antifungal tolerance in fungal pathogens

F Yang, J Berman - Current Opinion in Microbiology, 2024 - Elsevier
Fungal infections are increasing globally, causing alarmingly high mortality and economic
burden. In addition to antifungal resistance, other more subtle drug responses appear to …

[HTML][HTML] Deciphering antifungal and antibiofilm mechanisms of isobavachalcone against Cryptococcus neoformans through RNA-seq and functional analyses

W Qian, J Lu, C Gao, Q Liu, Y Li, Q Zeng, J Zhang… - Microbial Cell …, 2024 - Springer
Cryptococcus neoformans has been designated as critical fungal pathogens by the World
Health Organization, mainly due to limited treatment options and the prevalence of …

The multiple frontiers in the study of extracellular vesicles produced by fungi

ML Rodrigues, RC May, G Janbon - Microbes and Infection, 2023 - Elsevier
The production of extracellular vesicles (EVs) by fungi has been recognized for about a
decade. Here we discuss the roles played by fungal EVs in biofilm formation, antifungal …

Ergosterol promotes aggregation of natamycin in the yeast plasma membrane

M Szomek, V Akkerman, L Lauritsen, HL Walther… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Polyene macrolides are antifungal substances, which interact with cells in a sterol-
dependent manner. While being widely used, their mode of action is poorly understood …

[HTML][HTML] Fungal extracellular vesicle-mediated regulation: from virulence factor to clinical application

J Liu, X Hu - Frontiers in Microbiology, 2023 - frontiersin.org
Invasive fungal disease (IFD) poses a significant threat to immunocompromised patients and
remains a global challenge due to limited treatment options, high mortality and morbidity …

The Cryptococcus extracellular vesicle transcriptome

A Taheraly, C Maufrais, F Moyrand, J Colin, JY Coppee… - bioRxiv, 2023 - biorxiv.org
Extracellular vesicles (EVs) are now recognized as key players in the biology of numerous
organisms, including pathogenic fungi. However, studying EVs in these organisms remains …

[HTML][HTML] Protocol for separation of fungal extracellular vesicles using ultracentrifugation from solid medium cultures

AC Piffer, FCG Reis, F Moyrand, B Montalvão… - STAR protocols, 2024 - Elsevier
Extracellular vesicles (EVs) have been identified in diverse fungi, including human
pathogens. In this protocol, we present two techniques for isolating and analyzing fungal …