Malaria is the most devastating parasitic infection in the world, annually causing over 1
million deaths and extensive morbidity. The global burden of malaria has increased over the …

Background Open access to databases of information generated by the research community
can synergize individual efforts and are epitomized by the genome mapping projects. Open …

Several new fluorescence malaria in vitro drug susceptibility microtiter plate assays that
detect the presence of malarial DNA in infected erythrocytes have recently been reported, in …

Malaria persists as an undiminished global problem, but the resources available to address
it have increased. Many tools for understanding its biology and epidemiology are well …

Antimalarial chemotherapy is one of the main pillars in the prevention and control of malaria.
Following widespread resistance of Plasmodium falciparum to chloroquine, sulfadoxine …

Abstract In 2006, artemether–lumefantrine (AL) became the first-line treatment of
uncomplicated malaria in Senegal, Mali, and the Gambia. To monitor its efficacy, between …

Background Anti-malarial drugs play a critical role in reducing malaria morbidity and
mortality, but their role is mediated by their effectiveness. Effectiveness is defined as the …

Background. The emergence and spread of drug resistance to current antimalarial therapies
remains a pressing concern, escalating the need for compounds that demonstrate novel …

We have developed a robust, fully automated anti-parasitic drug-screening method that
selects compounds specifically targeting parasite enzymes and not their host counterparts …

Background The exacting nutritional requirements and complicated life cycles of parasites
mean that they are not always amenable to high-throughput drug screening using …