Vaccine adjuvants: mechanisms and platforms
T Zhao, Y Cai, Y Jiang, X He, Y Wei, Y Yu… - Signal transduction and …, 2023 - nature.com
Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …
Peptide hydrogels as immunomaterials and their use in cancer immunotherapy delivery
Peptide‐based hydrogel biomaterials have emerged as an excellent strategy for immune
system modulation. Peptide‐based hydrogels are supramolecular materials that self …
system modulation. Peptide‐based hydrogels are supramolecular materials that self …
RNA origami functions as a self-adjuvanted nanovaccine platform for cancer immunotherapy
Peptide-based vaccines have been widely investigated in cancer immunotherapy. Despite
their high specificity, safety, and low production cost, these vaccines have shown limited …
their high specificity, safety, and low production cost, these vaccines have shown limited …
Injectable Nano-in-Gel Vaccine for Spatial and Temporal Control of Vaccine Kinetics and Breast Cancer Postsurgical Therapy
T Liu, X Si, L Liu, S Ma, Z Huang, Y Zhang, W Song… - ACS …, 2024 - ACS Publications
Breast cancer is the most commonly diagnosed cancer, and surgical resection is the first
choice for its treatment. With the development of operation techniques, surgical treatment for …
choice for its treatment. With the development of operation techniques, surgical treatment for …
Gene therapy for urea cycle defects: An update from historical perspectives to future prospects
C Duff, IE Alexander, J Baruteau - Journal of Inherited …, 2024 - Wiley Online Library
Urea cycle defects (UCDs) are severe inherited metabolic diseases with high unmet needs
which present a permanent risk of hyperammonaemic decompensation and subsequent …
which present a permanent risk of hyperammonaemic decompensation and subsequent …
Responsive microneedles as a new platform for precision immunotherapy
X Liu, H Song, T Sun, H Wang - Pharmaceutics, 2023 - mdpi.com
Microneedles are a well-known transdermal or transdermal drug delivery system. Different
from intramuscular injection, intravenous injection, etc., the microneedle delivery system …
from intramuscular injection, intravenous injection, etc., the microneedle delivery system …
Broad and Durable Humoral Responses Following Single Hydrogel Immunization of SARS‐CoV‐2 Subunit Vaccine
Most vaccines require several immunizations to induce robust immunity, and indeed, most
SARS‐CoV‐2 vaccines require an initial two‐shot regimen followed by several boosters to …
SARS‐CoV‐2 vaccines require an initial two‐shot regimen followed by several boosters to …
Enhancing the effect of nucleic acid vaccines in the treatment of HPV-related cancers: an overview of delivery systems
IA de Moura, AJD Silva, LS de Macêdo, MCV Invenção… - Pathogens, 2022 - mdpi.com
Prophylactic vaccines against human papillomavirus (HPV) have proven efficacy in those
who have not been infected by the virus. However, they do not benefit patients with …
who have not been infected by the virus. However, they do not benefit patients with …
Lung metastasis-Harnessed in-Situ adherent porous organic nanosponge-mediated antigen capture for A self-cascaded detained dendritic cells and T cell infiltration
TH Wu, YJ Lu, MR Chiang, PH Chen, YS Lee, MY Shen… - Biomaterials, 2024 - Elsevier
The infiltration of cytotoxic T lymphocytes promises to suppress the most irresistible
metastatic tumor for immunotherapy, yet immune privilege and low immunogenic responses …
metastatic tumor for immunotherapy, yet immune privilege and low immunogenic responses …
A scalable synthesis of adjuvanting antigen depots based on metal–organic frameworks
RN Ehrman, OR Brohlin, YH Wijesundara… - Chemical …, 2024 - pubs.rsc.org
Vaccines have saved countless lives by preventing and even irradicating infectious
diseases. Commonly used subunit vaccines comprising one or multiple recombinant …
diseases. Commonly used subunit vaccines comprising one or multiple recombinant …