Connexin 43 (Cx43) is the primary gap junction protein of mammalian heart ventricles and is
encoded by the gene Gja1 which has a single coding exon and therefore cannot be spliced …

Abstract Lead (Pb) and arsenic (As) are prevalent metal contaminants in the environment.
Exposures to these metals are associated with impaired neuronal functions and adverse …

Mouse hepatitis virus (MHV)-induced murine neuroinflammation serves as a model to study
acute meningoencephalomyelitis, hepatitis, and chronic neuroinflammatory demyelination; …

This review focuses on connexins and nexus or gap junctions in the genesis, progression,
and therapy of carcinomas of the human urinary tract. Some decades ago, the idea was born …

Arsenic is known as a well-established human carcinogen. Gap Junction Protein Alpha 1
(GJA1) is a multifunction protein that forms gap junction channels and is important for …

Simple Summary Uranium, a fuel material widely used for nuclear reaction and a source of
nuclear weapons, is an emerging pollutant threatening human health. This study …

Background: Gadolinium chloride (GdCl3) has been reported to attenuate liver injury caused
by a variety of toxicants. Gap junctional intercellular communication (GJIC) is thought to be …

Chronic exposure to environmental pollutants threatens human health. Arsenic, a world-
wide diffused toxicant, is associated to cardiac pathology in the adult and to congenital heart …

RSA59 preincubated with NBE into the mouse brain significantly reduces acute hepatitis,
meningoencephalomyelitis, and chronic progressive demyelination. Additionally, NBE …

Developmental life is a very sensitive time window of the new organism, including our
species, during which both maternal and external environment can profoundly influence its …