Evaluation of the Effect of Macrocyclic Ring Size on [203Pb]Pb(II) Complex Stability in Pyridyl-Containing Chelators
BL McNeil, KJ Kadassery, AW McDonagh… - Inorganic …, 2022 - ACS Publications
As an element-equivalent theranostic pair, lead-203 (203Pb, 100% EC, half-life= 51.92 h)
and lead-212 (212Pb, 100% β–, half-life= 10.64 h), through the emission of γ rays and an α …
and lead-212 (212Pb, 100% β–, half-life= 10.64 h), through the emission of γ rays and an α …
[HTML][HTML] Exploring the use of rigid 18-membered macrocycles with amide pendant arms for Pb (ii)-based radiopharmaceuticals
C Harriswangler, BL McNeil… - Inorganic Chemistry …, 2024 - pubs.rsc.org
We report a detailed investigation on the use of chelators PYTAM, H4PYTAMGly, CHX-
PYTAM and H4CHX-PYTAMGly for the complexation of Pb (II)-radioisotopes with potential …
PYTAM and H4CHX-PYTAMGly for the complexation of Pb (II)-radioisotopes with potential …
[HTML][HTML] EANM guidance document: dosimetry for first-in-human studies and early phase clinical trials
C Stokke, S Gnesin, J Tran-Gia, F Cicone… - European Journal of …, 2024 - Springer
The numbers of diagnostic and therapeutic nuclear medicine agents under investigation are
rapidly increasing. Both novel emitters and novel carrier molecules require careful selection …
rapidly increasing. Both novel emitters and novel carrier molecules require careful selection …
Comparative Study of a Decadentate Acyclic Chelate, HOPO-O10, and Its Octadentate Analogue, HOPO-O8, for Radiopharmaceutical Applications
I Carbo-Bague, C Li, BL McNeil, Y Gao… - Inorganic …, 2023 - ACS Publications
Radiolanthanides and actinides are aptly suited for the diagnosis and treatment of cancer
via nuclear medicine because they possess unique chemical and physical properties (eg …
via nuclear medicine because they possess unique chemical and physical properties (eg …
Evaluated and recommended cross-section data for production of radionuclides with emerging interest in nuclear medicine imaging. Part 1: Positron emission …
A Hermanne, FT Tárkányi, AV Ignatyuk… - Nuclear Instruments and …, 2023 - Elsevier
Evaluated reactions for production of thirteen radionuclides with emerging interest for use in
PET imaging are reported. Experimental cross section data for 53 possible production routes …
PET imaging are reported. Experimental cross section data for 53 possible production routes …
SPECT imaging of 226Ac as a theranostic isotope for 225Ac radiopharmaceutical development
H Koniar, C Rodríguez-Rodríguez… - Physics in Medicine …, 2022 - iopscience.iop.org
Objective. The development of alpha-emitting radiopharmaceuticals using 225 Ac (t ½= 9.92
d) benefits from the quantitative determination of its biodistribution and is not always easy to …
d) benefits from the quantitative determination of its biodistribution and is not always easy to …
[HTML][HTML] PET imaging of the neurotensin targeting peptide NOTA-NT-20.3 using cobalt-55, copper-64 and gallium-68
Introduction: Neurotensin receptor 1 (NTSR1) is an emerging target for imaging and therapy
of many types of cancer. Nuclear imaging of NTSR1 allows for noninvasive assessment of …
of many types of cancer. Nuclear imaging of NTSR1 allows for noninvasive assessment of …
Development of the occupational exposure during the production and application of radiopharmaceuticals in Germany
J Vogt, U Oeh, FJ Maringer - Journal of Radiological Protection, 2024 - iopscience.iop.org
An increasing number of radiopharmaceuticals and proteins are available for diagnosing
and treating various diseases. The demand for existing and newly developed …
and treating various diseases. The demand for existing and newly developed …
[HTML][HTML] Biodistribution and radiation dosimetry of multiple tracers on total-body positron emission tomography/computed tomography
L Li, L Wan, H Zhao, C Wang, W Wei… - Quantitative Imaging in …, 2023 - ncbi.nlm.nih.gov
Background [18 F] F-FDG,[68 Ga] Ga-PSMA-11, and [68 Ga] Ga-FAPI-04 have achieved
good results in multiple clinical trials and clinical practice, but the imaging of these tracers is …
good results in multiple clinical trials and clinical practice, but the imaging of these tracers is …
Theranostic Surrogacy of [123I]NaI for Differentiated Thyroid Cancer Radionuclide Therapy
SB Kim, MS Lee, IH Song, HS Park… - Molecular …, 2023 - ACS Publications
Precise dosimetry has gained interest for interpreting the response assessments of novel
therapeutic radiopharmaceuticals, as well as for improving conventional radiotherapies such …
therapeutic radiopharmaceuticals, as well as for improving conventional radiotherapies such …